Dr. John Isaac, M.D

NPI: 1295799005
Total Payments
$2.3M
2024 Payments
$199,532
Companies
65
Transactions
4,293
Medicare Patients
23,579
Medicare Billing
$7.1M

Payment Breakdown by Category

Other$1.9M (81.4%)
Travel$238,970 (10.4%)
Consulting$98,874 (4.3%)
Food & Beverage$88,961 (3.9%)
Education$108.16 (0.0%)

Payments by Nature

Nature of Payment Amount Transactions Share
Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program $1.9M 715 80.9%
Travel and Lodging $238,970 1,226 10.4%
Consulting Fee $98,874 42 4.3%
Food and Beverage $88,961 2,295 3.9%
Honoraria $12,000 3 0.5%
Education $108.16 12 0.0%

Top Paying Companies

Company Total Records Latest Year
Esperion Therapeutics, Inc. $355,569 409 $0 (2024)
Amgen Inc. $311,908 573 $0 (2024)
AstraZeneca Pharmaceuticals LP $247,897 325 $0 (2024)
SANOFI-AVENTIS U.S. LLC $244,875 332 $0 (2024)
Boehringer Ingelheim Pharmaceuticals, Inc. $178,718 241 $0 (2024)
Janssen Pharmaceuticals, Inc $145,567 333 $0 (2024)
E.R. Squibb & Sons, L.L.C. $137,341 308 $0 (2024)
Regeneron Healthcare Solutions, Inc. $128,093 196 $0 (2024)
Novartis Pharmaceuticals Corporation $121,331 275 $0 (2024)
Amarin Pharma Inc. $103,856 210 $0 (2023)

Payment History by Year

Year Amount Transactions Top Company
2024 $199,532 417 Esperion Therapeutics, Inc. ($50,449)
2023 $140,389 396 E.R. Squibb & Sons, L.L.C. ($30,003)
2022 $283,273 486 Esperion Therapeutics, Inc. ($107,092)
2021 $273,072 449 Esperion Therapeutics, Inc. ($153,074)
2020 $233,187 415 AstraZeneca Pharmaceuticals LP ($81,642)
2019 $435,390 717 SANOFI-AVENTIS U.S. LLC ($110,246)
2018 $392,599 709 Regeneron Healthcare Solutions, Inc. ($67,048)
2017 $336,452 704 Amgen Inc. ($79,355)

All Payment Transactions

4,293 individual payment records from CMS Open Payments — Page 1 of 172

Date Company Product Nature Form Amount Type
12/27/2024 Boston Scientific Corporation WATCHMAN Access System (Device) Travel and Lodging Cash or cash equivalent $120.15 General
Category: WATCHMAN_IC
12/20/2024 Kiniksa Pharmaceuticals International, plc Arcalyst (Drug) Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program Cash or cash equivalent $5,400.00 General
Category: Rheumatology
12/20/2024 Kiniksa Pharmaceuticals International, plc Arcalyst (Drug) Travel and Lodging Cash or cash equivalent $140.05 General
Category: Rheumatology
12/19/2024 Novo Nordisk Inc Wegovy (Drug) Food and Beverage In-kind items and services $24.02 General
Category: Obesity
12/18/2024 Merck Sharp & Dohme LLC VERQUVO (Drug), VERQUVO Food and Beverage In-kind items and services $20.93 General
Category: CARDIOVASCULAR
12/18/2024 PFIZER INC. ELIQUIS (Drug), NURTEC ODT Food and Beverage In-kind items and services $7.32 General
Category: CARDIOVASCULAR;METABOLIC DISEASE
12/13/2024 Alnylam Pharmaceuticals Inc. Food and Beverage In-kind items and services $31.41 General
12/12/2024 Novo Nordisk Inc Ozempic (Drug), Rybelsus Food and Beverage In-kind items and services $7.42 General
Category: Diabetes
12/11/2024 Novartis Pharmaceuticals Corporation ENTRESTO (Drug), LEQVIO Food and Beverage In-kind items and services $23.76 General
Category: Cardiology/Vascular Diseases
12/05/2024 PFIZER INC. ELIQUIS (Drug) Food and Beverage In-kind items and services $132.00 General
Category: CARDIOVASCULAR;METABOLIC DISEASE
12/04/2024 AstraZeneca Pharmaceuticals LP FARXIGA (Drug) Food and Beverage In-kind items and services $14.05 General
Category: Cardiovascular and Metabolism
12/02/2024 Kiniksa Pharmaceuticals International, plc Arcalyst (Drug) Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program Cash or cash equivalent $600.00 General
Category: Rheumatology
12/02/2024 Novo Nordisk Inc Ozempic (Drug), Rybelsus Food and Beverage In-kind items and services $17.03 General
Category: Diabetes
11/26/2024 Boston Scientific Corporation WATCHMAN FLX (Device) Food and Beverage In-kind items and services $26.38 General
Category: WATCHMAN FLX_IC
11/25/2024 E.R. Squibb & Sons, L.L.C. CAMZYOS (Drug) Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program Cash or cash equivalent $2,604.00 General
Category: Cardiovascular
11/25/2024 Lilly USA, LLC JARDIANCE (Drug) Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program Cash or cash equivalent $1,250.00 General
Category: Diabetes
11/20/2024 Amgen Inc. Repatha (Biological) Food and Beverage In-kind items and services $13.58 General
Category: Cardiology
11/19/2024 Regeneron Healthcare Solutions, Inc. EVKEEZA (Biological) Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program Cash or cash equivalent $3,696.00 General
Category: CARDIOVASCULAR AND METABOLISM
11/19/2024 PFIZER INC. VYNDAQEL (Drug) Food and Beverage In-kind items and services $22.87 General
Category: CARDIOVASCULAR
11/18/2024 Amgen Inc. Repatha (Biological) Travel and Lodging Cash or cash equivalent $16.08 General
Category: Cardiology
11/18/2024 Amgen Inc. Repatha (Biological) Travel and Lodging Cash or cash equivalent $5.00 General
Category: Cardiology
11/14/2024 Regeneron Healthcare Solutions, Inc. EVKEEZA (Biological) Food and Beverage In-kind items and services $121.82 General
Category: CARDIOVASCULAR AND METABOLISM
11/13/2024 Kiniksa Pharmaceuticals International, plc Arcalyst (Drug) Food and Beverage In-kind items and services $41.67 General
Category: Rheumatology
11/13/2024 Novartis Pharmaceuticals Corporation ENTRESTO (Drug), LEQVIO Food and Beverage In-kind items and services $22.47 General
Category: Cardiology/Vascular Diseases
11/12/2024 Amgen Inc. Repatha (Biological) Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program Cash or cash equivalent $2,800.00 General
Category: Cardiology

Medicare Billing by Year

Year Procedures Beneficiaries Services Submitted Medicare Paid
2023 39 6,143 10,572 $8.1M $2.0M
2022 39 5,801 9,673 $7.4M $1.8M
2021 38 6,117 10,144 $7.9M $2.1M
2020 37 5,518 9,106 $5.5M $1.3M
Total Patients
23,579
Total Services
39,495
Medicare Billing
$7.1M
Procedure Codes
157

All Medicare Procedures & Services

157 procedure records from CMS Medicare Utilization — Page 1 of 7

HCPCS Description Setting Year Patients Services Charges Medicare Paid Ratio
78431 Nuclear medicine studies of blood flow in heart muscle at rest and with stress with concurrent ct scan Office 2023 398 398 $3.2M $786,280 24.7%
A9555 Rubidium rb-82, diagnostic, per study dose, up to 60 millicuries Office 2023 398 402 $327,180 $255,961 78.2%
99214 Established patient office or other outpatient visit, 30-39 minutes Office 2023 1,068 2,306 $922,400 $225,810 24.5%
33285 Insertion of heart rhythm monitor under skin Office 2023 35 35 $556,500 $126,000 22.6%
93306 Ultrasound of heart with color-depicted blood flow, rate, direction and valve function Office 2023 692 731 $950,300 $110,399 11.6%
93880 Ultrasound of both sides of head and neck blood flow Office 2023 606 608 $395,200 $93,893 23.8%
J2785 Injection, regadenoson, 0.1 mg Office 2023 465 1,860 $186,000 $79,358 42.7%
78452 Nuclear medicine studies of heart muscle at rest and with stress and spect Office 2023 151 152 $444,600 $53,605 12.1%
93015 Exercise or drug-induced heart stress test with electrocardiogram (ecg) with supervision and review by physician Office 2023 549 551 $190,145 $30,857 16.2%
93229 Electrocardiogram (ecg) up to 30 days continuous with transmission of patient triggered events with review and report by health care professional Office 2023 38 38 $83,600 $26,202 31.3%
G2066 Interrogation device evaluation(s), (remote) up to 30 days; implantable cardiovascular physiologic monitor system, implantable loop recorder system, or subcutaneous cardiac rhythm monitor system, remote data acquisition(s), receipt of transmissions and tec Office 2023 90 709 $102,805 $19,808 19.3%
93298 Evaluation of cardiac rhythm monitor system, remote up to 30 days Office 2023 91 710 $88,750 $14,139 15.9%
93241 Heart rhythm recording, analysis, report, review, and interpretation of continous external ekg over more than 48 hours up to 7 days Office 2023 62 64 $57,600 $13,662 23.7%
99204 New patient office or other outpatient visit, 45-59 minutes Office 2023 109 109 $57,225 $12,495 21.8%
99232 Subsequent hospital care with moderate levelof medical decision making, if using time, at least 35 minutes Facility 2023 97 170 $24,650 $11,079 44.9%
99215 Established patient office or other outpatient visit, 40-54 minutes Office 2023 68 76 $42,940 $10,591 24.7%
93925 Ultrasound of leg arteries or artery grafts Office 2023 52 52 $36,760 $10,289 28.0%
A9500 Technetium tc-99m sestamibi, diagnostic, per study dose Office 2023 146 148 $12,013 $9,420 78.4%
92928 Insertion of stents with balloon dilation of coronary artery or branch, single artery or branch Facility 2023 18 20 $66,000 $9,282 14.1%
93458 Insertion of tube in left lower heart chamber and coronary artery for diagnosis with review by radiologist Facility 2023 37 39 $97,500 $7,285 7.5%
99222 Initial hospital care with straightforward or low-level medical decision making, if using time, at least 55 minutes Facility 2023 63 64 $17,280 $6,798 39.3%
93970 Ultrasound study of arm or leg veins with compression and maneuvers Office 2023 36 37 $22,200 $5,718 25.8%
99443 Telephone medical discussion with physician, 21-30 minutes Office 2023 49 55 $27,500 $5,705 20.7%
95723 Measurement of brain wave activity (eeg), 61-84 hours with health care professional review and report Office 2023 28 28 $19,320 $5,666 29.3%
99233 Subsequent hospital care with moderate levelof medical decision making, if using time, at least 50 minutes Facility 2023 32 54 $10,260 $5,312 51.8%

About Dr. John Isaac, M.D

Dr. John Isaac, M.D is a Interventional Cardiology healthcare provider based in Houston, Texas. This provider has been registered with the National Plan and Provider Enumeration System (NPPES) since 04/17/2006. The National Provider Identifier (NPI) number assigned to this provider is 1295799005.

According to the Centers for Medicare & Medicaid Services (CMS) Open Payments database, Dr. John Isaac, M.D has received a total of $2.3M in payments from pharmaceutical and medical device companies, with $199,532 received in 2024. These payments were reported across 4,293 transactions from 65 companies. The most common payment nature is "Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program" ($1.9M).

As a Medicare-enrolled provider, Isaac has provided services to 23,579 Medicare beneficiaries, totaling 39,495 services with total Medicare billing of $7.1M. Data is available for 4 years (2020–2023), covering 157 distinct procedure/service records.

Practice Information

  • Specialty Interventional Cardiology
  • Other Specialties Cardiovascular Disease
  • Location Houston, TX
  • Active Since 04/17/2006
  • Last Updated 10/25/2016
  • Taxonomy Code 207RI0011X
  • Entity Type Individual
  • NPI Number 1295799005

Products in Payments

  • NEXLIZET (Drug) $339,477
  • Repatha (Biological) $311,123
  • JARDIANCE (Drug) $246,884
  • PRALUENT (Drug) $223,203
  • XARELTO (Drug) $145,645
  • BRILINTA (Drug) $133,167
  • ENTRESTO (Drug) $120,364
  • Vascepa (Drug) $103,856
  • FARXIGA (Drug) $102,837
  • ELIQUIS (Drug) $95,517
  • PRALUENT ALIROCUMAB INJECTION (Biological) $91,212
  • CAMZYOS (Drug) $73,699
  • Arcalyst (Drug) $66,788
  • CHANTIX (Drug) $34,042
  • PRALUENT (Biological) $22,442
  • NEXLETOL (Drug) $16,092
  • EVKEEZA (Biological) $14,726
  • ZONTIVITY (Drug) $14,681
  • Optimizer (Device) $14,243
  • Roszet (Drug) $13,751

Data Sources

Provider data from NPPES. Payment data from CMS Open Payments. Medicare data from CMS Medicare Provider Utilization. All data is public and updated periodically.

Interventional Cardiology Doctors in Houston