XPOVIO

Drug Karyopharm Therapeutics Inc.
Total Payments
$46.3M
Transactions
31,225
Doctors
7,608
Companies
1

Payment Trends by Year

Year Amount Transactions Doctors
2024 $5.0M 7,062 2,874
2023 $7.0M 7,241 3,286
2022 $9.8M 6,517 2,925
2021 $12.6M 5,936 2,261
2020 $11.8M 4,469 1,753

Payments by Nature

Nature of Payment Amount Transactions Share
Unspecified $39.0M 6,499 84.4%
Honoraria $4.5M 1,540 9.7%
Consulting Fee $1.1M 464 2.3%
Food and Beverage $602,075 20,925 1.3%
Travel and Lodging $570,945 1,058 1.2%
Space rental or facility fees (teaching hospital only) $182,200 56 0.4%
Charitable Contribution $150,000 1 0.3%
Grant $70,000 3 0.2%
Education $61,781 659 0.1%
Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program $53,953 13 0.1%
Compensation for serving as faculty or as a speaker for a medical education program $14,175 7 0.0%

Payments by Type

Research
$39.0M
6,499 transactions
General
$7.2M
24,726 transactions

Research Studies & Clinical Trials

Study Name Sponsor Amount Doctors
A Phase 1/2 Study of Selinexor in Combination with SOC Therapy for Newly Diagnosed or Recurrent Glioblastoma Karyopharm Therapeutics Inc. $5.0M 0
XPORT-COV-1001 Karyopharm Therapeutics Inc. $3.5M 0
A Phase 2 Study to Evaluate the Efficacy and Safety of Selinexor in Patients with High-Risk Myelofibrosis Karyopharm Therapeutics Inc. $2.3M 0
A Randomized, Double-Blind, Phase 3 Trial of Maintenance with Selinexor/Placebo After Combination Chemotherapy for Patients with Advanced or Recurrent Endometrial Cancer Karyopharm Therapeutics Inc. $2.1M 1
Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination with Multiple Standard Chemotherapy Agents in Patients with Advanced Malignancies Karyopharm Therapeutics Inc. $1.9M 0
A Phase 3, Randomized, Placebo-Controlled, Double-Blind, Multicenter Trial of Selinexor in Maintenance Therapy After Systemic Therapy for Patients With p53 Wild-Type, Advanced or Recurrent Endometrial Carcinoma Karyopharm Therapeutics Inc. $1.8M 0
A phase 2 open-label multicenter study to evaluate the safety and efficacy of selinexor + pembrolizumab in recurrent advanced melanoma Karyopharm Therapeutics Inc. $1.8M 0
KCP-330-020 Karyopharm Therapeutics Inc. $1.7M 0
A Phase 2-3 Multicenter, Randomized, Double-blind Study of Selinexor (KPT-330) versus Placebo in Patients with Advanced Unresectable Dedifferentiated Liposarcoma (DDLS) Karyopharm Therapeutics Inc. $1.7M 0
A Phase 1b/2 Study of Selinexor (KPT-330) in Combination with Backbone Treatments for Resistant/Refractory Multiple Myeloma Karyopharm Therapeutics Inc. $1.6M 0
A PHASE 2 OPEN-LABEL MULTICENTER STUDY TO EVALUATE THE SAFETY AND EFFICACY OF SELINEXOR WITH OR WITHOUT PEMBROLIZUMAB VERSUS STANDARD OF CARE IN PREVIOUSLY TREATED METASTATIC COLORECTAL CANCER WITH RAS MUTATIONS Karyopharm Therapeutics Inc. $1.0M 0
A Phase 2B study of selinexor (KPT-330), in combination with carfilzomib, daratumumab or pomalidomide in patients with multiple myeloma relapsing on current therapy Karyopharm Therapeutics Inc. $983,226 0
KCP-330-017A Karyopharm Therapeutics Inc. $831,280 0
A Phase 1/2 Study of Selinexor in Combination With Standard of Care (SoC) Therapy for Newly Diagnosed or Recurrent Glioblastoma Karyopharm Therapeutics Inc. $828,550 0
A Phase 2/3, Multicenter, Randomized, Study of Rituximab-Gemcitabine-Dexamethasone-Platinum (R-GDP) With or Without Selinexor in Patients with Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL) Karyopharm Therapeutics Inc. $784,107 0
KCP-330-024 Karyopharm Therapeutics Inc. $625,379 0
A phase 2, randomized, open-label, multicenter study of Selinexor or Physicians choice in patients with myelofibrosis Karyopharm Therapeutics Inc. $589,757 0
3300012 Karyopharm Therapeutics Inc. $585,610 0
Phase 1/2 Trial of Selinexor in COmbination with Carfilzomib, Pomalidomide and DexamethasonE (SCOPE) for Patients with Proteasome-inhibitor and Immunomodulatory Drug Refractory Multiple Myeloma Karyopharm Therapeutics Inc. $562,224 0
KCP-330-012 Karyopharm Therapeutics Inc. $539,046 0

Top Doctors Receiving Payments for XPOVIO — Page 2

Doctor Specialty Location Total Records
, MD Hematology Iowa City, IA $67,347 34
, M.D Medical Oncology New York, NY $66,975 29
, MD Hematology & Oncology Philadelphia, PA $63,788 41
, M.D Hematology & Oncology Dyer, IN $61,928 44
, M.D Hematology Dallas, TX $54,870 44
, MD Medical Oncology Mcallen, TX $53,996 29
, MD Medical Oncology Kansas City, KS $52,616 34
, M.D Hematology & Oncology Pittsburgh, PA $48,416 31
, M.D Medical Oncology Dallas, TX $47,949 30
, M.D Hematology & Oncology San Antonio, TX $47,009 25
, MD Hematology Washington, DC $44,315 30
, APRN Adult Health Chicago, IL $42,176 71
, M.D Hematology Scottsdale, AZ $42,011 11
, M.D Specialist Canton, OH $40,874 27
, MD Hematology & Oncology Pikeville, KY $39,065 34
, M.D Hematology & Oncology Houston, TX $37,794 20
, MD Hematology & Oncology Gilbert, AZ $37,598 27
, MD Hematology & Oncology Milwaukee, WI $36,737 14
, M.D Internal Medicine Fort Collins, CO $34,859 26
, M.D Family Medicine Omaha, NE $33,752 11
, M.D Specialist Pasadena, CA $33,421 41
, M.D Hematology & Oncology Scottsdale, AZ $32,449 22
, APRN Nurse Practitioner Omaha, NE $32,216 55
, MD Hematology & Oncology New York, NY $31,701 23
, RN MSN APN Oncology Hackensack, NJ $31,147 50

About XPOVIO

XPOVIO is a drug associated with $46.3M in payments to 7,608 healthcare providers, recorded across 31,225 transactions in the CMS Open Payments database. The primary manufacturer is Karyopharm Therapeutics Inc..

Payment data is available from 2020 to 2024. In 2024, $5.0M was paid across 7,062 transactions to 2,874 doctors.

The most common payment nature for XPOVIO is "Unspecified" ($39.0M, 84.4% of total).

XPOVIO is associated with 20 research studies, including "A Phase 1/2 Study of Selinexor in Combination with SOC Therapy for Newly Diagnosed or Recurrent Glioblastoma" ($5.0M).