Karyopharm Therapeutics Inc.

Pharmaceutical & medical device company payment data from CMS Open Payments.

Total Payments
$48.6M
Doctors Paid
7,608
Transactions
31,668
2024 Total
$5.6M

Payment Breakdown by Category

Research$41.4M (85.1%)
Consulting$1.1M (2.2%)
Food & Beverage$602,075 (1.2%)
Travel$570,945 (1.2%)

Payments by Nature

Nature of Payment Amount Transactions Share
Unspecified $41.4M 6,942 85.1%
Honoraria $4.5M 1,540 9.2%
Consulting Fee $1.1M 464 2.2%
Food and Beverage $602,075 20,925 1.2%
Travel and Lodging $570,945 1,058 1.2%
Space rental or facility fees (teaching hospital only) $182,200 56 0.4%
Charitable Contribution $150,000 1 0.3%
Grant $70,000 3 0.1%
Education $61,781 659 0.1%
Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program $53,953 13 0.1%
Compensation for serving as faculty or as a speaker for a medical education program $14,175 7 0.0%

Payments by Type

Research
$41.4M
6,942 transactions
General
$7.2M
24,726 transactions

Research Studies & Clinical Trials

Study Name Total Paid Doctors Records
A Phase 1/2 Study of Selinexor in Combination with SOC Therapy for Newly Diagnosed or Recurrent Glioblastoma $5.0M 0 1,778
XPORT-COV-1001 $3.5M 0 261
A Phase 2 Study to Evaluate the Efficacy and Safety of Selinexor in Patients with High-Risk Myelofibrosis $2.3M 0 666
A Randomized, Double-Blind, Phase 3 Trial of Maintenance with Selinexor/Placebo After Combination Chemotherapy for Patients with Advanced or Recurrent Endometrial Cancer $2.1M 1 697
Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination with Multiple Standard Chemotherapy Agents in Patients with Advanced Malignancies $1.9M 0 6
A Phase 3, Randomized, Placebo-Controlled, Double-Blind, Multicenter Trial of Selinexor in Maintenance Therapy After Systemic Therapy for Patients With p53 Wild-Type, Advanced or Recurrent Endometrial Carcinoma $1.8M 0 335
A phase 2 open-label multicenter study to evaluate the safety and efficacy of selinexor + pembrolizumab in recurrent advanced melanoma $1.8M 0 324
KCP-330-020 $1.7M 0 286
A Phase 2-3 Multicenter, Randomized, Double-blind Study of Selinexor (KPT-330) versus Placebo in Patients with Advanced Unresectable Dedifferentiated Liposarcoma (DDLS) $1.7M 0 306
A Phase 1b/2 Study of Selinexor (KPT-330) in Combination with Backbone Treatments for Resistant/Refractory Multiple Myeloma $1.6M 0 257
A Phase 1/2 Open-Label Study of the Safety, Tolerability and Efficacy of the Selective Inhibitor of Nuclear Export (SINE) Compound KPT-8602 in Patients with Relapsed, Refractory Cancer Indications $1.6M 1 199
A PHASE 2 OPEN-LABEL MULTICENTER STUDY TO EVALUATE THE SAFETY AND EFFICACY OF SELINEXOR WITH OR WITHOUT PEMBROLIZUMAB VERSUS STANDARD OF CARE IN PREVIOUSLY TREATED METASTATIC COLORECTAL CANCER WITH RAS MUTATIONS $1.0M 0 51
A Phase 3 Randomized, Open-label Trial of Selinexor, Pomalidomide, and Dexamethasone (SPd) Versus Elotuzumab, Pomalidomide, and Dexamethasone (EloPd) in Patients With Relapsed or Refractory Multiple Myeloma (RRMM) $1.0M 0 253
A Phase 2B study of selinexor (KPT-330), in combination with carfilzomib, daratumumab or pomalidomide in patients with multiple myeloma relapsing on current therapy $983,226 0 6
KCP-330-017A $831,280 0 118
A Phase 1/2 Study of Selinexor in Combination With Standard of Care (SoC) Therapy for Newly Diagnosed or Recurrent Glioblastoma $828,550 0 82
A Phase 2/3, Multicenter, Randomized, Study of Rituximab-Gemcitabine-Dexamethasone-Platinum (R-GDP) With or Without Selinexor in Patients with Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL) $784,107 0 219
KCP-330-024 $625,379 0 189
A phase 2, randomized, open-label, multicenter study of Selinexor or Physicians choice in patients with myelofibrosis $589,757 0 82
3300012 $585,610 0 1
Phase 1/2 Trial of Selinexor in COmbination with Carfilzomib, Pomalidomide and DexamethasonE (SCOPE) for Patients with Proteasome-inhibitor and Immunomodulatory Drug Refractory Multiple Myeloma $562,224 0 5
KCP-330-012 $539,046 0 52
A Phase 2 Randomized Single-Blind Study to Evaluate the Activity and Safety of Low Dose Oral Selinexor (KPT-330) in Patients with Severe COVID-19 iNFECTION $530,833 0 126
A Multicenter, Phase 1/2 Study of Selinexor in Combination with Backbone Treatments or Novel Therapies in Patients with Relapsed or Refractory Diffuse Large B-cell Lymphoma $484,371 0 24
A PHASE 1 OPEN-LABEL STUDY OF KPT-9274 IN PATIENTS WITH RELAPSED AND REFRACTORY ACUTE MYELOID LEUKEMIA $400,000 0 2
Part I: A Phase 2b, Open-Label, Single-Arm Study of Selinexor (KPT-330) plus Dexamethasone in Patients with Multiple Myeloma Exposed to Bortezomib, Carfilzomib, Lenalidomide and Pomalidomide and Refractory to an IMiD and a Proteasome Inhibitor.Part II: A Phase 2b, Open Label, Single-Arm Study of Selinexor (KPT-330), Plus Low Dose Dexamethasone (Sd) in Patients with Multiple Myeloma Previously Treated with Lenalidomide, Pomalidomide, Bortezomib, Carfilzomib, and Daratumumab and Refractory to Pri $379,577 0 67
Phase Ib trial of Low-Dose Selinexor (KPT-330) in combination with Choline Salicylate (CS) for the treatment of patients with residual/relapsed/refractory non-Hodgkin lymphoma (NHL) $340,788 0 14
KCP-330-023 $336,950 0 134
Evaluating the impact of novel inhibitors of nuclear pore export in SLE $321,028 0 5
A Phase 3 Randomized Controlled, Open-Label Study of Selinexor, Bortezomib, and Dexamethasone (SVd) Versus Bortezomib and Dexamethasone (Vd) in Patients with Relapsed or Refractory Multiple Myeloma (RRMM) $286,225 2 118

Payments by Medical Specialty

Specialty Total Paid Doctors Avg/Doctor
Hematology & Oncology $2.8M 2,137 $1,292
Medical Oncology $1.6M 508 $3,175
Internal Medicine $875,571 739 $1,185
Hematology $506,844 243 $2,086
Specialist $270,981 147 $1,843
Nurse Practitioner $154,577 638 $242.28
Family $125,870 913 $137.86
Gynecologic Oncology $70,453 63 $1,118
Adult Health $69,008 217 $318.01
Physician Assistant $52,358 451 $116.09
Acute Care $51,672 127 $406.87
Family Medicine $45,947 62 $741.09
Oncology $33,648 43 $782.50
Student in an Organized Health Care Education/Training Program $19,829 195 $101.69
Neurology $17,904 7 $2,558
Pediatric Hematology-Oncology $16,852 4 $4,213
Military Health Care Provider $13,935 3 $4,645
Medical $12,218 171 $71.45
Hospice and Palliative Medicine $12,077 22 $548.96
Registered Nurse First Assistant $9,330 2 $4,665
Obstetrics & Gynecology $9,315 41 $227.19
Radiation Oncology $8,484 198 $42.85
Registered Nurse $7,891 104 $75.88
Infectious Disease $6,874 6 $1,146
Gerontology $6,465 70 $92.36
Surgical Oncology $5,879 11 $534.44
Surgery $3,321 47 $70.65
Gynecology $3,265 3 $1,088
Primary Care $3,142 36 $87.29
Pulmonary Disease $2,899 7 $414.08
Hospitalist $2,689 33 $81.48
Independent Medical Examiner $1,977 1 $1,977
Critical Care Medicine $1,386 21 $65.99
General Practice $1,373 19 $72.27
Diagnostic Radiology $1,261 29 $43.47
Pediatrics $1,062 17 $62.44
Women's Health $929.23 10 $92.92
Surgical $903.73 16 $56.48
Nurse Anesthetist, Certified Registered $678.37 6 $113.06
Podiatrist $655.00 1 $655.00
Anatomic Pathology & Clinical Pathology $475.78 9 $52.86
Emergency Medicine $467.87 13 $35.99
Legal Medicine $465.40 2 $232.70
Anesthesiology $443.98 7 $63.43
Clinical Nurse Specialist $396.59 9 $44.07
Dermatology $319.29 8 $39.91
Urology $286.73 7 $40.96
Pain Medicine $284.05 5 $56.81
Geriatric Medicine $279.43 3 $93.14
Psychiatry $265.41 5 $53.08
Cardiovascular Disease $249.00 8 $31.13
Chiropractor $247.19 4 $61.80
Therapeutic Radiology $231.28 5 $46.26
Gastroenterology $224.85 6 $37.48
Emergency $223.39 5 $44.68
Neuroscience $219.63 1 $219.63
Thoracic Surgery (Cardiothoracic Vascular Surgery) $202.71 5 $40.54
Community Health $187.18 2 $93.59
Ambulatory Care $183.33 1 $183.33
Rheumatology $182.04 7 $26.01
General Acute Care Hospital $164.82 3 $54.94
Dental Hygienist $161.44 1 $161.44
Otolaryngology $157.58 2 $78.79
Neonatal $154.75 2 $77.38
Medical-Surgical $154.70 2 $77.35
Clinical Pathology/Laboratory Medicine $149.88 3 $49.96
Nephrology $147.32 4 $36.83
Emergency Medical Services $134.01 1 $134.01
Psychiatric/Mental Health $132.60 3 $44.20
Neuroradiology $125.63 1 $125.63
Low Vision Rehabilitation $125.00 1 $125.00
Adult Medicine $124.96 1 $124.96
Surgical Critical Care $120.86 1 $120.86
Blood Banking & Transfusion Medicine $119.76 1 $119.76
Psychiatric/Mental Health, Adult $114.74 1 $114.74
Sports Physician $112.80 1 $112.80
Transplant Surgery $110.02 1 $110.02
Colon & Rectal Surgery $99.21 1 $99.21
Prosthodontics $96.01 1 $96.01
Interventional Pain Medicine $89.18 1 $89.18
Licensed Practical Nurse $63.18 2 $31.59
Clinical Cytogenetics $62.51 1 $62.51
Optometrist $62.11 3 $20.70
Endocrinology, Diabetes & Metabolism $62.06 2 $31.03
Dentist $56.44 2 $28.22
Body Imaging $53.91 2 $26.96
Obstetrics $53.50 2 $26.75
Home Health $53.26 1 $53.26
Physical Medicine & Rehabilitation $52.47 2 $26.24
Procedural Dermatology $51.20 1 $51.20
Medical Specialty $45.33 1 $45.33
Orthopaedic Surgery $42.39 3 $14.13
Allergy $38.80 2 $19.40
Infusion Therapy $37.40 2 $18.70
Home Health Aide $37.22 1 $37.22
Reproductive Endocrinology $35.13 1 $35.13
Plastic Surgery $34.40 1 $34.40
Cytopathology $34.13 1 $34.13
Genetic Counselor, MS $33.11 1 $33.11
Sports Medicine $32.71 2 $16.36
Women's Health Care, Ambulatory $32.35 1 $32.35
Diagnostic Ultrasound $32.14 1 $32.14
Neuromusculoskeletal Medicine & OMM $31.49 1 $31.49
Clinical Cardiac Electrophysiology $28.46 1 $28.46
Neurological Surgery $27.32 2 $13.66
Anesthesiologist Assistant $25.21 1 $25.21
Nuclear Imaging & Therapy $22.90 1 $22.90
Single Specialty $22.54 1 $22.54
Behavior Technician $19.99 1 $19.99
Allergy & Immunology $15.22 1 $15.22
Advanced Practice Midwife $14.73 1 $14.73
Adolescent Medicine $12.37 1 $12.37
Ophthalmology $11.52 1 $11.52

Top Paid Doctors

Doctor Specialty Location Total 2024
Hakan Kaya, M.d, M.D Medical Oncology Spokane, WA $516,436 $0
Mohammadbagher Ziari, Md, MD Hematology & Oncology Corona, CA $275,557 $0
Kelly Mccaul, M.d, M.D Hematology & Oncology Sioux Falls, SD $229,465 $0
Ehsan Malek, M.d, M.D Medical Oncology Buffalo, NY $189,256 $0
Dr. Moshe Levy, Md, MD Medical Oncology Dallas, TX $170,316 $0
Dr. James Berenson, M.d, M.D Specialist West Hollywood, CA $167,083 $0
Dr. Kevin Kelly, M.d, M.D Hematology & Oncology Los Angeles, CA $139,915 $0
Rajesh Behl, M.d, M.D Hematology & Oncology Berkeley, CA $138,418 $0
Cristina Gasparetto, M.d, M.D Hematology & Oncology Durham, NC $136,662 $0
Taral Patel, Md, MD Medical Oncology Columbus, OH $134,316 $0
Dr. Rahul Naik, M.d, M.D Internal Medicine Los Angeles, CA $125,316 $0
Dr. Robert Vescio, M.d, M.D Hematology & Oncology Los Angeles, CA $120,763 $0
Dr. Joseph Mikhael, M.d, M.D Hematology Scottsdale, AZ $120,192 $0
Dr. Daniel Landau, Md, MD Hematology & Oncology Orlando, FL $101,943 $0
Mojtaba Akhtari, M.d, M.D Internal Medicine Omaha, NE $93,199 $0
Dr. Binod Dhakal, Md, MD Internal Medicine Milwaukee, WI $85,718 $0
Michael Schuster, Md, MD Internal Medicine New York, NY $84,452 $0
Dr. Bruce Cheson, Md, MD Hematology & Oncology Bethesda, MD $82,920 $0
Dr. Hardeep Phull, Md, MD Internal Medicine Escondido, CA $82,821 $0
Hamza Hashmi, M.d, M.D Internal Medicine Charleston, SC $80,574 $0
Tarek Chidiac, Md, MD Medical Oncology Columbus, OH $76,955 $0
Dr. Christopher Maisel, Md, MD Hematology & Oncology Dallas, TX $76,002 $0
Kasra Karamlou, M.d, M.D Hematology & Oncology Sandusky, OH $72,997 $0
Ralph Boccia, M.d, M.D Medical Oncology Bethesda, MD $71,108 $0
Yogesh Jethava, Md, MD Hematology Park Ridge, IL $67,347 $0

Top Products

  • XPOVIO $46.3M

Associated Products (1)

Payment Categories

  • Food & Beverage $602,075
  • Consulting $1.1M
  • Travel & Lodging $570,945
  • Research $41.4M

About Karyopharm Therapeutics Inc.

Karyopharm Therapeutics Inc. has made $48.6M in payments to 7,608 healthcare providers, recorded across 31,668 transactions in the CMS Open Payments database. In 2024, the company paid $5.6M. The top product by payment volume is XPOVIO ($46.3M).

Payments were distributed across 113 medical specialties. The top specialty by payment amount is Hematology & Oncology ($2.8M to 2,137 doctors).

Payment categories include: Food & Beverage ($602,075), Consulting ($1.1M), Research ($41.4M), Travel & Lodging ($570,945).

Karyopharm Therapeutics Inc. is associated with 1 products in the CMS Open Payments database.