TYSABRI

Biological Biogen, Inc.
Total Payments
$44.4M
Transactions
138,972
Doctors
9,573
Companies
1

Payment Trends by Year

Year Amount Transactions Doctors
2024 $1.3M 9,998 2,858
2023 $466,004 14,365 3,766
2022 $3.7M 18,533 3,846
2021 $5.3M 17,109 3,757
2020 $10.1M 8,238 2,099
2019 $11.3M 18,307 3,547
2018 $7.2M 26,063 3,494
2017 $5.0M 26,359 3,492

Payments by Nature

Nature of Payment Amount Transactions Share
Unspecified $25.0M 2,771 56.3%
Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program $10.1M 3,532 22.7%
Consulting Fee $5.6M 2,977 12.6%
Food and Beverage $2.4M 122,891 5.4%
Travel and Lodging $1.3M 5,289 2.9%
Education $57,436 1,512 0.1%

Payments by Type

Research
$25.0M
2,771 transactions
General
$19.4M
136,201 transactions

Research Studies & Clinical Trials

Study Name Sponsor Amount Doctors
A Study to Evaluate Efficacy, Safety, and Tolerability of EID of Natalizumab (BG00002) in Participants With RRMS Switching From Treatment With Natalizumab SID in Relation to Continued SID Treatment- Followed by Extension Study Comprising SC and IV Natalizumab Administration Biogen, Inc. $7.6M 0
A Study to Evaluate Efficacy, Safety, and Tolerability of 6-Week Extended Interval Dosing of Natalizumab (BG00002) in Participants With Relapsing-Remitting Multiple Sclerosis (RRMS) Switching From Treatment With 4-Week Natalizumab Standard Interval Dosing (SID) in Relation to Continued SID Treatment Biogen, Inc. $5.1M 0
Phase 2 Efficacy, Safety, and Tolerability Study of Natalizumab in Focal Epilepsy Biogen, Inc. $3.6M 25
Observational Study of Tysabri in Early Relapsing-Remitting Multiple Sclerosis in Anti-JC Virus Antibody Negative Participants Biogen, Inc. $1.5M 0
Safety and Efficacy of Intravenous Natalizumab in Acute Ischemic Stroke Biogen, Inc. $1.3M 3
A Randomized, Controlled, Open-Label, Rater-Blinded, Phase 3b Study of the Efficacy, Safety, and Tolerability of 6-Week Extended Interval Dosing of Natalizumab (BG00002) in Subjects With Relapsing-Remitting Multiple SclerosisSwitching From Treatment With 4-Week Natalizumab Standard Interval Dosing (SID) in Relation to Continued SID Treatment Biogen, Inc. $1.0M 0
Natalizumab for use in Patients with High Risk Graft Versus Host Disease (GVHD) Biogen, Inc. $919,119 0
US-TYS-14-10669- Natalizumab for use in Patients with High Risk Graft Versus Host Disease (GVHD) Biogen, Inc. $611,820 0
EID Columbia and NYU SRA Biogen, Inc. $274,866 0
Comparison of Tysabri, Vumerity, and Ocrevus in MS Patients Stable on Therapy to Characterize Divergent Proteomic, Radiomic, and Clinical Trajectories Biogen, Inc. $255,129 0
US-TYS-18-11393 (Foley): Evaluation of Extended Interval Dosing of Natalizumab Efficacy: Retrospective MRI Review (AOP 19-164) Biogen, Inc. $242,760 0
Single-center retrospective safety analysis of multiple sclerosis patients treated with high efficacy disease modifying therapies Biogen, Inc. $222,539 0
Phase I/II Study of the Use of Tysabri in the Treatment of Graft-vs-Host Disease Biogen, Inc. $204,000 0
Multiple Sclerosis Partners Advancing Technology and Health Solutions (MS PATHS) - TOUCH Data Linkage Sub-study Biogen, Inc. $174,330 0
Long-term outcomes of multiple sclerosis patients on extended interval dosing of Natalizumab Biogen, Inc. $172,417 0
Does Long Term Natalizumab Therapy Normalize Brain Atrophy Rates and QOL in RRMS? (A Longitudinal Study Using Whole Brain, Neocortical and Subcortical, Atrophy Rates and Patient Reported Outcomes) Biogen, Inc. $151,459 0
EXTENDED INTERVAL DOSING SCHEDULES FOR NATALIZUMAB: RETROSPECTIVE REGISTRIES Biogen, Inc. $139,847 0
US-TYS-18-11394 - Evaluation of Extended Interval Dosing of Natalizumab Efficacy: Retrospective MRI Review Biogen, Inc. $137,946 0
Real-world experience of using Tysabri in 750 MS patients over 15 years in a single US center in the absence of PML - focusing on unique clinical practice in evolution of risk mitigating strategies. Biogen, Inc. $115,215 1
Single Tysabri Infusion for Anterior Ischemic Optic Neuropathies and Central Retinal Artery Occlusions Caused by Giant Cell Arteritis Biogen, Inc. $89,941 0

Top Doctors Receiving Payments for TYSABRI — Page 3

Doctor Specialty Location Total Records
, MD Neurology Atlanta, GA $89,330 104
, MD Neurology Pompano Beach, FL $87,516 238
, MD Neurology Denver, CO $87,333 179
, M.D Neurology Los Angeles, CA $87,000 87
, M.D Neurology Atlanta, GA $86,584 124
, D.O Neurology Centerville, OH $85,829 108
, M.D Student in an Organized Health Care Education/Training Program Cleveland, OH $83,401 58
, M.D Neurology San Diego, CA $81,492 138
, M.D Neurology Minneapolis, MN $80,426 88
, MD Neurology San Juan, PR $78,655 149
, M.D Neurology Jasper, IN $78,605 91
, MD Specialist Mineola, NY $78,088 105
, MD Neurology Chicago, IL $77,488 73
, MD Neurology Naples, FL $76,609 151
, MD Neurology Norwich, CT $76,384 199
, MD PHD Neurology Ann Arbor, MI $76,379 84
, MD Neurology Seattle, WA $75,936 59
, D.O Neurology Farmington Hills, MI $75,536 155
, M.D Neurology Scottsdale, AZ $74,309 98
, MD Neurology Brighton, MA $73,852 163
, MD Neurology New Hyde Park, NY $73,836 195
, M.D Neurology Atlanta, GA $72,638 123
, MD Neurology Pittsburgh, PA $72,292 47
, M.D Neurology Washington, DC $71,680 66
, DO Neurology Hinsdale, IL $70,987 173

About TYSABRI

TYSABRI is a biological associated with $44.4M in payments to 9,573 healthcare providers, recorded across 138,972 transactions in the CMS Open Payments database. The primary manufacturer is Biogen, Inc..

Payment data is available from 2017 to 2024. In 2024, $1.3M was paid across 9,998 transactions to 2,858 doctors.

The most common payment nature for TYSABRI is "Unspecified" ($25.0M, 56.3% of total).

TYSABRI is associated with 20 research studies, including "A Study to Evaluate Efficacy, Safety, and Tolerability of EID of Natalizumab (BG00002) in Participants With RRMS Switching From Treatment With Natalizumab SID in Relation to Continued SID Treatment- Followed by Extension Study Comprising SC and IV Natalizumab Administration" ($7.6M).