TYSABRI

Biological Biogen, Inc.
Total Payments
$44.4M
Transactions
138,972
Doctors
9,573
Companies
1

Payment Trends by Year

Year Amount Transactions Doctors
2024 $1.3M 9,998 2,858
2023 $466,004 14,365 3,766
2022 $3.7M 18,533 3,846
2021 $5.3M 17,109 3,757
2020 $10.1M 8,238 2,099
2019 $11.3M 18,307 3,547
2018 $7.2M 26,063 3,494
2017 $5.0M 26,359 3,492

Payments by Nature

Nature of Payment Amount Transactions Share
Unspecified $25.0M 2,771 56.3%
Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program $10.1M 3,532 22.7%
Consulting Fee $5.6M 2,977 12.6%
Food and Beverage $2.4M 122,891 5.4%
Travel and Lodging $1.3M 5,289 2.9%
Education $57,436 1,512 0.1%

Payments by Type

Research
$25.0M
2,771 transactions
General
$19.4M
136,201 transactions

Research Studies & Clinical Trials

Study Name Sponsor Amount Doctors
A Study to Evaluate Efficacy, Safety, and Tolerability of EID of Natalizumab (BG00002) in Participants With RRMS Switching From Treatment With Natalizumab SID in Relation to Continued SID Treatment- Followed by Extension Study Comprising SC and IV Natalizumab Administration Biogen, Inc. $7.6M 0
A Study to Evaluate Efficacy, Safety, and Tolerability of 6-Week Extended Interval Dosing of Natalizumab (BG00002) in Participants With Relapsing-Remitting Multiple Sclerosis (RRMS) Switching From Treatment With 4-Week Natalizumab Standard Interval Dosing (SID) in Relation to Continued SID Treatment Biogen, Inc. $5.1M 0
Phase 2 Efficacy, Safety, and Tolerability Study of Natalizumab in Focal Epilepsy Biogen, Inc. $3.6M 25
Observational Study of Tysabri in Early Relapsing-Remitting Multiple Sclerosis in Anti-JC Virus Antibody Negative Participants Biogen, Inc. $1.5M 0
Safety and Efficacy of Intravenous Natalizumab in Acute Ischemic Stroke Biogen, Inc. $1.3M 3
A Randomized, Controlled, Open-Label, Rater-Blinded, Phase 3b Study of the Efficacy, Safety, and Tolerability of 6-Week Extended Interval Dosing of Natalizumab (BG00002) in Subjects With Relapsing-Remitting Multiple SclerosisSwitching From Treatment With 4-Week Natalizumab Standard Interval Dosing (SID) in Relation to Continued SID Treatment Biogen, Inc. $1.0M 0
Natalizumab for use in Patients with High Risk Graft Versus Host Disease (GVHD) Biogen, Inc. $919,119 0
US-TYS-14-10669- Natalizumab for use in Patients with High Risk Graft Versus Host Disease (GVHD) Biogen, Inc. $611,820 0
EID Columbia and NYU SRA Biogen, Inc. $274,866 0
Comparison of Tysabri, Vumerity, and Ocrevus in MS Patients Stable on Therapy to Characterize Divergent Proteomic, Radiomic, and Clinical Trajectories Biogen, Inc. $255,129 0
US-TYS-18-11393 (Foley): Evaluation of Extended Interval Dosing of Natalizumab Efficacy: Retrospective MRI Review (AOP 19-164) Biogen, Inc. $242,760 0
Single-center retrospective safety analysis of multiple sclerosis patients treated with high efficacy disease modifying therapies Biogen, Inc. $222,539 0
Phase I/II Study of the Use of Tysabri in the Treatment of Graft-vs-Host Disease Biogen, Inc. $204,000 0
Multiple Sclerosis Partners Advancing Technology and Health Solutions (MS PATHS) - TOUCH Data Linkage Sub-study Biogen, Inc. $174,330 0
Long-term outcomes of multiple sclerosis patients on extended interval dosing of Natalizumab Biogen, Inc. $172,417 0
Does Long Term Natalizumab Therapy Normalize Brain Atrophy Rates and QOL in RRMS? (A Longitudinal Study Using Whole Brain, Neocortical and Subcortical, Atrophy Rates and Patient Reported Outcomes) Biogen, Inc. $151,459 0
EXTENDED INTERVAL DOSING SCHEDULES FOR NATALIZUMAB: RETROSPECTIVE REGISTRIES Biogen, Inc. $139,847 0
US-TYS-18-11394 - Evaluation of Extended Interval Dosing of Natalizumab Efficacy: Retrospective MRI Review Biogen, Inc. $137,946 0
Real-world experience of using Tysabri in 750 MS patients over 15 years in a single US center in the absence of PML - focusing on unique clinical practice in evolution of risk mitigating strategies. Biogen, Inc. $115,215 1
Single Tysabri Infusion for Anterior Ischemic Optic Neuropathies and Central Retinal Artery Occlusions Caused by Giant Cell Arteritis Biogen, Inc. $89,941 0

Top Doctors Receiving Payments for TYSABRI

Doctor Specialty Location Total Records
Jason King Oklahoma City, OK $24.7M 2,581
, MD Neurology Los Angeles, CA $488,849 524
, MD Neurology Vienna, VA $426,938 690
, DO Neurology Dublin, OH $382,765 434
, M.D Neurology Milwaukee, WI $359,474 206
, M.D Neurology Newport Beach, CA $253,128 298
, M.D Specialist Guaynabo, PR $191,626 378
, M.D Neurology Chicago, IL $187,244 118
, MD Neurology Amarillo, TX $183,069 267
, M.D Neurology Cincinnati, OH $173,097 147
, MD Neurology Albuquerque, NM $165,970 155
, MD Neurology Santa Barbara, CA $164,725 165
, M.D Neurology Tampa, FL $152,954 211
, M.D Neurology Salt Lake Cty, UT $150,637 279
Douglas Jeffery Huntersville, NC $141,899 187
, MD Neurology Phoenix, AZ $138,681 173
, M.D Neurology Reno, NV $138,445 202
, M.D Neurology Winchester, VA $135,753 414
, M.D Neurology Bethpage, NY $129,380 136
, MD Neurology Knoxville, TN $127,771 171
, M.D Neurology Staten Island, NY $126,550 227
Peter Wade Hartford, CT $125,992 160
, MD Specialist Carrollton, VA $123,437 158
, M.D. PH.D Neurology Round Rock, TX $118,078 113
, M.D Neurology Overland Park, KS $116,503 318

About TYSABRI

TYSABRI is a biological associated with $44.4M in payments to 9,573 healthcare providers, recorded across 138,972 transactions in the CMS Open Payments database. The primary manufacturer is Biogen, Inc..

Payment data is available from 2017 to 2024. In 2024, $1.3M was paid across 9,998 transactions to 2,858 doctors.

The most common payment nature for TYSABRI is "Unspecified" ($25.0M, 56.3% of total).

TYSABRI is associated with 20 research studies, including "A Study to Evaluate Efficacy, Safety, and Tolerability of EID of Natalizumab (BG00002) in Participants With RRMS Switching From Treatment With Natalizumab SID in Relation to Continued SID Treatment- Followed by Extension Study Comprising SC and IV Natalizumab Administration" ($7.6M).