GIVLAARI

Drug Alnylam Pharmaceuticals Inc.
Total Payments
$3.5M
Transactions
11,031
Doctors
6,377
Companies
1

Payment Trends by Year

Year Amount Transactions Doctors
2024 $172,209 2,697 2,081
2023 $263,133 3,337 2,241
2022 $989,052 2,386 1,686
2021 $976,053 1,897 1,278
2020 $747,944 624 379
2019 $389,237 90 0

Payments by Nature

Nature of Payment Amount Transactions Share
Unspecified $2.7M 445 75.0%
Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program $267,635 163 7.6%
Consulting Fee $263,891 104 7.5%
Food and Beverage $243,352 10,119 6.9%
Space rental or facility fees (teaching hospital only) $60,250 24 1.7%
Travel and Lodging $42,405 157 1.2%
Grant $7,500 1 0.2%
Education $1,132 18 0.0%

Payments by Type

Research
$2.7M
445 transactions
General
$886,165
10,586 transactions

Research Studies & Clinical Trials

Study Name Sponsor Amount Doctors
ENVISION: A Study to Evaluate the Efficacy and Safety of Givosiran (ALN-AS1) in Patients With Acute Hepatic Porphyrias (AHP) Alnylam Pharmaceuticals Inc. $1.1M 0
INSIGHT-AHP A Study to Characterize the Prevalence of Acute Hepatic Porphyria AHP in Patients With Clinical Presentation and History Consistent With AHP Alnylam Pharmaceuticals Inc. $314,261 0
A Study to Evaluate Long-term Safety and Clinical Activity of Givosiran (ALN-AS1) in Patient With Acute Intermittent Porphyria (AIP) Alnylam Pharmaceuticals Inc. $235,508 0
ELEVATE, a Registry of Patients With Acute Hepatic Porphyria (AHP) Alnylam Pharmaceuticals Inc. $212,563 0
Reducing diagnostic delays in Acute Hepatic Porphyria using a machine learning approach Alnylam Pharmaceuticals Inc. $178,693 0
International Porphyria Diagnostic Database Alnylam Pharmaceuticals Inc. $109,116 0
ELEVATE, a Global Observational Longitudinal Prospective Registry of Patients With Acute Hepatic Porphyria (AHP) Alnylam Pharmaceuticals Inc. $89,335 0
TESTING FOR ACUTE HEPATIC PORPHYRIA IN CYCLIC VOMITING SYNDROME Alnylam Pharmaceuticals Inc. $76,750 0
EXPLORE A Natural History Study of Acute Hepatic Porphyria AHP Alnylam Pharmaceuticals Inc. $74,976 0
Expanded Access Protocol ofGivosiranfor Patients With Acute Hepatic Porphyria Alnylam Pharmaceuticals Inc. $56,762 0
Prevalence of acute porphyria (AP) in young women presenting to an emergency department (ED) with prolonged or recurrent /unexplained abdominal pain Alnylam Pharmaceuticals Inc. $56,500 0
Prevalence of acute porphyria (AP) in young women presenting to an emergency department (ED) with prolonged or recurrent /unexplained abdominal pain. Alnylam Pharmaceuticals Inc. $56,500 0
EXPLORE: A Natural History Study of Acute Hepatic Porphyria (AHP) Alnylam Pharmaceuticals Inc. $34,483 0
Estimating the Frequency and Neuro-Hormonal Characteristics of Acute Hepatic Porphyria in Postural Tachycardia Syndrome Alnylam Pharmaceuticals Inc. $6,890 0
A Multicenter, Open-label Extension Study to Evaluate the Long-term Safey and Clinical Activity of Subcutaneously Adminstered ALN-AS1 in Patients with Acute Intermittent Porphyria who have Completed a Previous Clinical study with ALN-AS1 Alnylam Pharmaceuticals Inc. $5,300 0
ELEVATE, a Registry of Patients With Acute Hepatic Porphyria (AHP) (ELEVATE) Alnylam Pharmaceuticals Inc. $990.00 0
INSIGHT-AHP: A Study to Characterize the Prevalence of Acute Hepatic Porphyria (AHP) in Patients With Clinical Presentation and History Consistent With AHP Alnylam Pharmaceuticals Inc. $294.00 0

Top Doctors Receiving Payments for GIVLAARI

Doctor Specialty Location Total Records
Unknown Charlotte, NC $2.7M 475
, MD Gastroenterology Houston, TX $47,044 47
, M.D., PH.D Emergency Medical Services New York, NY $47,000 48
, M.D Gastroenterology San Francisco, CA $44,798 47
, MD PHD Clinical Genetics (M.D.) Cleveland, OH $44,403 51
Sean Rudnick Gastroenterology Winston Salem, NC $21,835 19
, MD Internal Medicine Gilbert, AZ $20,723 14
, M.D., M.S Clinical Genetics (M.D.) New York, NY $20,448 7
, M.D Hepatology Philadelphia, PA $18,530 16
, MD Pulmonary Disease Boston, MA $18,513 29
, PA-C Medical Layton, UT $16,958 44
, M.D Hematology & Oncology San Antonio, TX $14,266 14
, M.D Internal Medicine Oklahoma City, OK $13,983 11
, MD Internal Medicine Ann Arbor, MI $13,234 8
, M.D Hematology & Oncology Little Rock, AR $13,065 6
, M.D Hematology Los Angeles, CA $12,923 21
, MD Gastroenterology Winston Salem, NC $12,582 27
, M.D Neurology Portland, OR $10,409 5
, MD Gastroenterology Galveston, TX $10,276 5
, MD Gastroenterology Memphis, TN $10,211 10
, MD Neurology Boston, MA $10,117 12
, M.D Internal Medicine Los Angeles, CA $8,319 4
, M.D Internal Medicine Chestnut Hill, MA $8,173 4
, MD Gastroenterology St. Louis, MO $7,776 4
, MD Neurology Birmingham, AL $6,942 8

About GIVLAARI

GIVLAARI is a drug associated with $3.5M in payments to 6,377 healthcare providers, recorded across 11,031 transactions in the CMS Open Payments database. The primary manufacturer is Alnylam Pharmaceuticals Inc..

Payment data is available from 2019 to 2024. In 2024, $172,209 was paid across 2,697 transactions to 2,081 doctors.

The most common payment nature for GIVLAARI is "Unspecified" ($2.7M, 75.0% of total).

GIVLAARI is associated with 17 research studies, including "ENVISION: A Study to Evaluate the Efficacy and Safety of Givosiran (ALN-AS1) in Patients With Acute Hepatic Porphyrias (AHP)" ($1.1M).