Dr. Dean Karalis, MD

NPI: 1609849256
Total Payments
$760,521
2024 Payments
$41,912
Companies
15
Transactions
613
Medicare Patients
5,685
Medicare Billing
$707,666

Payment Breakdown by Category

Other$579,947 (76.3%)
Travel$76,640 (10.1%)
Consulting$73,859 (9.7%)
Research$15,044 (2.0%)
Food & Beverage$14,811 (1.9%)
Education$220.32 (0.0%)

Payments by Nature

Nature of Payment Amount Transactions Share
Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program $579,947 182 76.3%
Travel and Lodging $76,640 202 10.1%
Consulting Fee $73,859 23 9.7%
Unspecified $15,044 8 2.0%
Food and Beverage $14,811 189 1.9%
Education $220.32 9 0.0%

Payments by Type

General
$745,477
605 transactions
Research
$15,044
8 transactions

Top Paying Companies

Company Total Records Latest Year
SANOFI-AVENTIS U.S. LLC $291,769 212 $0 (2019)
Regeneron Healthcare Solutions, Inc. $203,047 180 $0 (2019)
Esperion Therapeutics, Inc. $137,032 111 $0 (2024)
Amarin Pharma Inc. $47,549 32 $0 (2022)
Novartis Pharmaceuticals Corporation $34,335 25 $0 (2024)
Regeneron Pharmaceuticals, Inc. $28,889 13 $0 (2024)
Amgen Inc. $13,100 27 $0 (2024)
AstraZeneca Pharmaceuticals LP $2,437 3 $0 (2021)
Alexion Pharmaceuticals, Inc. $1,960 1 $0 (2020)
IDORSIA PHARMACEUTICALS US INC $120.82 2 $0 (2024)

Payment History by Year

Year Amount Transactions Top Company
2024 $41,912 58 Esperion Therapeutics, Inc. ($25,820)
2023 $11,277 17 Novartis Pharmaceuticals Corporation ($8,921)
2022 $13,841 17 Esperion Therapeutics, Inc. ($11,151)
2021 $109,251 75 Esperion Therapeutics, Inc. ($79,290)
2020 $50,021 28 Esperion Therapeutics, Inc. ($18,800)
2019 $150,548 136 SANOFI-AVENTIS U.S. LLC ($101,917)
2018 $196,796 132 SANOFI-AVENTIS U.S. LLC ($94,940)
2017 $186,875 150 SANOFI-AVENTIS U.S. LLC ($94,912)

All Payment Transactions

613 individual payment records from CMS Open Payments — Page 1 of 25

Date Company Product Nature Form Amount Type
11/19/2024 Amgen Inc. Repatha (Biological) Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program Cash or cash equivalent $2,800.00 General
Category: Cardiology
11/16/2024 Amgen Inc. Repatha (Biological) Food and Beverage In-kind items and services $31.46 General
Category: Cardiology
11/13/2024 Amgen Inc. Repatha (Biological) Food and Beverage In-kind items and services $138.60 General
Category: Cardiology
11/06/2024 IDORSIA PHARMACEUTICALS US INC Tryvio (Drug) Education In-kind items and services $60.41 General
Category: Hypertension
11/05/2024 IDORSIA PHARMACEUTICALS US INC Tryvio (Drug) Education In-kind items and services $60.41 General
Category: Hypertension
10/15/2024 Novartis Pharmaceuticals Corporation LEQVIO (Drug) Consulting Fee Cash or cash equivalent $700.00 General
Category: Cardiology/Vascular Diseases
10/07/2024 Novo Nordisk Inc Wegovy (Drug) Food and Beverage In-kind items and services $23.28 General
Category: Obesity
10/03/2024 Kiniksa Pharmaceuticals International, plc Arcalyst (Drug) Food and Beverage In-kind items and services $24.44 General
Category: Not Applicable
10/02/2024 Esperion Therapeutics, Inc. NEXLIZET (Drug), NEXLETOL Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program Cash or cash equivalent $1,280.00 General
Category: ANTILIPEMIC AGENTS
09/17/2024 Alnylam Pharmaceuticals Inc. AMVUTTRA (Drug) Food and Beverage In-kind items and services $26.95 General
Category: Genetic Disease
08/14/2024 Amgen Inc. Repatha (Biological) Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program Cash or cash equivalent $2,800.00 General
Category: Cardiology
08/14/2024 Amgen Inc. Repatha (Biological) Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program Cash or cash equivalent $467.00 General
Category: Cardiology
08/07/2024 Amgen Inc. Repatha (Biological) Food and Beverage In-kind items and services $124.99 General
Category: Cardiology
08/01/2024 Esperion Therapeutics, Inc. NEXLIZET (Drug), NEXLETOL Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program Cash or cash equivalent $1,280.00 General
Category: ANTILIPEMIC AGENTS
07/18/2024 Esperion Therapeutics, Inc. NEXLIZET (Drug), NEXLETOL Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program Cash or cash equivalent $2,300.00 General
Category: ANTILIPEMIC AGENTS
07/15/2024 Amgen Inc. Repatha (Biological) Food and Beverage In-kind items and services $27.58 General
Category: Cardiology
07/10/2024 Esperion Therapeutics, Inc. NEXLIZET (Drug), NEXLETOL Travel and Lodging In-kind items and services $793.27 General
Category: ANTILIPEMIC AGENTS
07/10/2024 Esperion Therapeutics, Inc. NEXLIZET (Drug), NEXLETOL Food and Beverage In-kind items and services $125.00 General
Category: ANTILIPEMIC AGENTS
07/03/2024 Esperion Therapeutics, Inc. NEXLIZET (Drug), NEXLETOL Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program Cash or cash equivalent $2,300.00 General
Category: ANTILIPEMIC AGENTS
06/27/2024 Esperion Therapeutics, Inc. NEXLIZET (Drug), NEXLETOL Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program Cash or cash equivalent $2,300.00 General
Category: ANTILIPEMIC AGENTS
06/25/2024 Esperion Therapeutics, Inc. NEXLIZET (Drug), NEXLETOL Food and Beverage In-kind items and services $122.94 General
Category: ANTILIPEMIC AGENTS
06/25/2024 Esperion Therapeutics, Inc. NEXLIZET (Drug), NEXLETOL Travel and Lodging Cash or cash equivalent $58.60 General
Category: ANTILIPEMIC AGENTS
06/19/2024 Esperion Therapeutics, Inc. NEXLIZET (Drug), NEXLETOL Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program Cash or cash equivalent $2,300.00 General
Category: ANTILIPEMIC AGENTS
06/19/2024 Esperion Therapeutics, Inc. NEXLIZET (Drug), NEXLETOL Travel and Lodging In-kind items and services $968.50 General
Category: ANTILIPEMIC AGENTS
06/19/2024 Esperion Therapeutics, Inc. NEXLIZET (Drug), NEXLETOL Food and Beverage In-kind items and services $124.99 General
Category: ANTILIPEMIC AGENTS

Research Studies & Clinical Trials

Study Name Company Amount Records
PUBLICATION SUPPORT PROVIDED IN CONNECTION WITH INCLISARIN RESEARCH Novartis Pharmaceuticals Corporation $8,750 1
PRALUENT CLINICAL DEVELOPMENT PROGRAM Regeneron Pharmaceuticals, Inc. $3,137 2
Analysis of Accenture?s Predictive Health Intelligence Environment (PHIE) dataset SANOFI-AVENTIS U.S. LLC $1,628 2
Data were obtained from Accenture?s ?Predictive Health Intelligence Environment? (PHIE) electronic medical record database. SANOFI-AVENTIS U.S. LLC $835.00 2
Prescribing Patterns of Proprotein Convertase Subtilisin-Kexin Type 9 Inhibitors in Eligible Patients with Clinical Atherosclerotic Cardiovascular Disease or Heterozygous Familial Hypercholesterolemia SANOFI-AVENTIS U.S. LLC $694.30 1

Medicare Billing by Year

Year Procedures Beneficiaries Services Submitted Medicare Paid
2023 7 1,299 2,166 $553,595 $158,826
2022 8 1,332 2,254 $533,670 $169,994
2021 12 1,453 2,421 $546,620 $198,651
2020 13 1,601 2,230 $554,976 $180,195
Total Patients
5,685
Total Services
9,071
Medicare Billing
$707,666
Procedure Codes
40

All Medicare Procedures & Services

40 procedure records from CMS Medicare Utilization — Page 1 of 2

HCPCS Description Setting Year Patients Services Charges Medicare Paid Ratio
99214 Established patient office or other outpatient visit, 30-39 minutes Office 2023 461 904 $248,600 $84,046 33.8%
93306 Ultrasound of heart with color-depicted blood flow, rate, direction and valve function Office 2023 269 278 $190,430 $42,955 22.6%
99215 Established patient office or other outpatient visit, 40-54 minutes Office 2023 79 105 $36,750 $14,229 38.7%
93000 Routine electrocardiogram (ecg) using at least 12 leads with interpretation and report Office 2023 410 779 $54,530 $8,335 15.3%
99204 New patient office or other outpatient visit, 45-59 minutes Office 2023 33 33 $11,550 $3,896 33.7%
99232 Subsequent hospital care with moderate levelof medical decision making, if using time, at least 35 minutes Facility 2023 36 56 $7,280 $3,504 48.1%
99495 Transitional care management services for problem of at least moderate complexity Office 2023 11 11 $4,455 $1,861 41.8%
99214 Established patient office or other outpatient visit, 30-39 minutes Office 2022 464 1,010 $235,540 $95,161 40.4%
93306 Ultrasound of heart with color-depicted blood flow, rate, direction and valve function Office 2022 276 282 $193,170 $45,459 23.5%
99215 Established patient office or other outpatient visit, 40-54 minutes Office 2022 56 76 $22,230 $11,059 49.7%
93000 Routine electrocardiogram (ecg) using at least 12 leads with interpretation and report Office 2022 414 744 $52,100 $7,977 15.3%
99204 New patient office or other outpatient visit, 45-59 minutes Office 2022 36 36 $11,640 $4,236 36.4%
99232 Follow-up hospital inpatient care per day, typically 25 minutes Facility 2022 40 59 $7,670 $3,173 41.4%
93015 Exercise or drug-induced heart stress test with electrocardiogram (ecg) with supervision and review by physician Office 2022 27 27 $8,550 $1,555 18.2%
99442 Telephone medical discussion with physician, 11-20 minutes Office 2022 19 20 $2,770 $1,374 49.6%
99214 Established patient outpatient visit, total time 30-39 minutes Office 2021 419 937 $173,345 $92,982 53.6%
93306 Ultrasound examination of heart including color-depicted blood flow rate, direction, and valve function Office 2021 341 348 $238,380 $58,217 24.4%
99215 Established patient outpatient visit, total time 40-54 minutes Office 2021 86 110 $28,050 $15,592 55.6%
93000 Routine ekg using at least 12 leads including interpretation and report Office 2021 399 662 $46,340 $7,648 16.5%
78452 Nuclear medicine study of vessels of heart using drugs or exercise multiple studies Office 2021 14 14 $16,030 $5,962 37.2%
99204 New patient outpatient visit, total time 45-59 minutes Office 2021 39 39 $11,310 $5,396 47.7%
99442 Physician telephone patient service, 11-20 minutes of medical discussion Office 2021 48 54 $6,750 $3,896 57.7%
99443 Physician telephone patient service, 21-30 minutes of medical discussion Office 2021 26 33 $5,940 $3,721 62.7%
99232 Subsequent hospital inpatient care, typically 25 minutes per day Facility 2021 43 63 $8,190 $3,692 45.1%
93015 Exercise or drug-induced heart and blood vessel stress test with ekg monitoring, physician supervision, interpretation, and report Office 2021 14 14 $6,300 $708.10 11.2%

About Dr. Dean Karalis, MD

Dr. Dean Karalis, MD is a Cardiovascular Disease healthcare provider based in Philadelphia, Pennsylvania. This provider has been registered with the National Plan and Provider Enumeration System (NPPES) since 02/13/2006. The National Provider Identifier (NPI) number assigned to this provider is 1609849256.

According to the Centers for Medicare & Medicaid Services (CMS) Open Payments database, Dr. Dean Karalis, MD has received a total of $760,521 in payments from pharmaceutical and medical device companies, with $41,912 received in 2024. These payments were reported across 613 transactions from 15 companies. The most common payment nature is "Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program" ($579,947).

As a Medicare-enrolled provider, Karalis has provided services to 5,685 Medicare beneficiaries, totaling 9,071 services with total Medicare billing of $707,666. Data is available for 4 years (2020–2023), covering 40 distinct procedure/service records.

Practice Information

  • Specialty Cardiovascular Disease
  • Location Philadelphia, PA
  • Active Since 02/13/2006
  • Last Updated 09/13/2025
  • Taxonomy Code 207RC0000X
  • Entity Type Individual
  • NPI Number 1609849256

Products in Payments

  • PRALUENT (Drug) $278,722
  • PRALUENT ALIROCUMAB INJECTION (Biological) $193,715
  • NEXLIZET (Drug) $135,573
  • Vascepa (Drug) $47,549
  • PRALUENT (Biological) $37,713
  • LEQVIO (Drug) $26,655
  • NO PRODUCT DISCUSSED (Drug) $13,047
  • Repatha (Biological) $12,874
  • FARXIGA (Drug) $2,417
  • NEXLETOL (Drug) $1,460
  • EVKEEZA (Biological) $506.87
  • Tryvio (Drug) $120.82
  • XARELTO (Drug) $70.15
  • AMVUTTRA (Drug) $26.95
  • Ozempic (Drug) $24.89
  • Arcalyst (Drug) $24.44
  • Wegovy (Drug) $23.28
  • BRILINTA (Drug) $19.95

Data Sources

Provider data from NPPES. Payment data from CMS Open Payments. Medicare data from CMS Medicare Provider Utilization. All data is public and updated periodically.

Cardiovascular Disease Doctors in Philadelphia