Kcentra

Biological CSL Behring
Total Payments
$56.0M
Transactions
36,456
Doctors
16,273
Companies
1

Payment Trends by Year

Year Amount Transactions Doctors
2024 $31.4M 8,349 4,742
2023 $15.5M 7,364 4,550
2022 $917,351 4,252 2,832
2021 $1.6M 3,290 2,029
2020 $867,572 2,093 1,322
2019 $2.5M 4,111 2,263
2018 $1.3M 3,593 1,957
2017 $2.0M 3,404 2,048

Payments by Nature

Nature of Payment Amount Transactions Share
Unspecified $50.8M 2,007 90.7%
Honoraria $1.9M 669 3.5%
Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program $1.6M 408 2.9%
Food and Beverage $892,896 28,281 1.6%
Travel and Lodging $582,648 1,962 1.0%
Education $72,184 3,107 0.1%
Consulting Fee $67,885 19 0.1%
Space rental or facility fees (teaching hospital only) $3,500 1 0.0%
Gift $26.50 2 0.0%

Payments by Type

Research
$50.8M
2,007 transactions
General
$5.2M
34,449 transactions

Research Studies & Clinical Trials

Study Name Sponsor Amount Doctors
A Prospective, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Large Simple Trial Evaluating the Use of BE1116 (4-Factor Prothrombin Complex Concentrate [Kcentra / Beriplex]) to Improve Survival in Patients With Traumatic Injury and Acute Major Bleeding CSL Behring $44.9M 0
An Observational Cohort Study of the Risk of Thromboembolic Events Among Adult Patients Treated With KCENTRA Compared With Plasma for Urgent Reversal of Vitamin K Antagonist Therapy in the Setting of Acute Major Bleeding CSL Behring $1.7M 0
IISKCENTRA CSL Behring $1.0M 0
A Prospective Randomized Controlled Trial on Pre-Hospital Use of Kcentra in Trauma Patients with Hemorrhagic Shock CSL Behring $1.0M 0
A Prospective Randomized Prehospital Trial Comparing Kcentra Plus Standard of Care to Standard of Care Alone in Trauma Patient With Hemorrhagic Shock CSL Behring $500,000 0
Risk of Thromboembolic Events Among Adults Treated with Kcentra vs. with Plasma for Urgent Reversal of Vitamin K Antagonist Therapy in the Setting of Acute Major Bleeding CSL Behring $410,742 0
Prehospital Kcentra for Hemorrhagic Shock IIS Pilot Trial CSL Behring $400,000 0
IIS KCENTRA CSL Behring $270,000 0
Cost Effective Analysis of Kcentra in Management of Gastrointestinal Bleeding in Coumadin-Treated Patients CSL Behring $114,000 0
Prothrombin Complex Concentrate (PCC) Compared to Fresh Frozen Plasma (FFP) for Post-cardiopulmonary Bypass Coagulopathy and Bleeding, a Prospective Randomized Trial at Large US Medical Center. CSL Behring $91,740 0
Optimized Administration of Prothrombin Complex Concentrate (PCC) vs. Standard Transfusion During/After Heart Transplantation - OPSTAHT CSL Behring $48,280 0
Administration of Prothrombin Complex Concentrate vs. Standard Transfusion DuringAfter Heart Transplantation OPSTAHT CSL Behring $42,744 0
Assessment of COAG Levels in LVAD Patients Following Tem Warfarin Reversal with Kcentra CSL Behring $37,917 0
BEnefits of Stroke Treatment Delivered Using a Mobile Stroke Unit Compared to Standard Management by Emergency Medical Services The BEST-MSU Study CSL Behring $37,477 0
Optimized administration of Prothrombin complex concentrate PCC vs. Standard Transfusion duringafter Heart Transplantation - OPSTAHT CSL Behring $36,120 0
Optimized Administration of Prothrombin Complex Concentrate PCC vs. Standard Transfusion DuringAfter Heart Transplantation - OPSTAHT CSL Behring $34,610 0
BEnefits of Stroke Treatment Delivered Using a Mobile Stroke Unit Compared to Standard Management by Emergency Medical Services:The BEST-MSU Study CSL Behring $31,735 0
Assessment of Coagulation Factor Levels in LVAD Patients Following Temporary Warfarin Reversal With 4F-PCC CSL Behring $30,313 0
Prothrombin complex concentrate compared to fresh frozen plasma for post-cardiopulminary bypass coagulopathy and bleeding, a prospective randomized trial at large US medical center. CSL Behring $29,139 0
Prothrombin Complex Concentrate PCC Compared to Fresh Frozen Plasma FFP for Post-cardiopulmonary Bypass Coagulopathy and Bleeding, a Prospective Randomized Trial at Large US Medical Center CSL Behring $23,207 0

Top Doctors Receiving Payments for Kcentra

Doctor Specialty Location Total Records
Unknown Virginia Beach, VA $50.8M 2,683
, MD Thoracic Surgery (Cardiothoracic Vascular Surgery) Tacoma, WA $617,864 584
, MD Emergency Medicine Williamsville, NY $499,451 504
, M.D Neurology Tampa, FL $463,728 459
, MD Anesthesiology Louisville, KY $343,060 395
, M.D Internal Medicine Livingston, NJ $302,953 277
, MD Surgery Columbus, OH $297,196 288
, MD Anesthesiology Englewood, NJ $285,897 250
, MD Emergency Medicine Philadelphia, PA $270,952 284
, MD Neurological Surgery Dallas, TX $229,131 193
, DO Specialist Columbus, OH $130,571 149
, D.O Personal Emergency Response Attendant Scottsdale, AZ $108,144 128
, M.D Internal Medicine Albany, NY $91,052 129
, MD Clinical Pathology Rochester, NY $75,842 69
, MD Emergency Medicine Cleveland, OH $58,196 79
, MD Neurology Cincinnati, OH $53,197 55
, M.D Neurology Chicago, IL $38,603 51
, MD Emergency Medical Services Austin, TX $34,114 12
, MD Clinical Pathology/Laboratory Medicine Atlanta, GA $33,514 49
, MD Hematology & Oncology Philadelphia, PA $30,501 4
, MD, PHD Emergency Medicine Boston, MA $25,792 18
John Holcomb Trauma Surgery Houston, TX $20,481 18
, MD Blood Banking & Transfusion Medicine Dallas, TX $17,920 5
Jan Jansen Trauma Surgery Birmingham, AL $17,816 6
, MD Surgery Portland, OR $16,764 25

About Kcentra

Kcentra is a biological associated with $56.0M in payments to 16,273 healthcare providers, recorded across 36,456 transactions in the CMS Open Payments database. The primary manufacturer is CSL Behring.

Payment data is available from 2017 to 2024. In 2024, $31.4M was paid across 8,349 transactions to 4,742 doctors.

The most common payment nature for Kcentra is "Unspecified" ($50.8M, 90.7% of total).

Kcentra is associated with 20 research studies, including "A Prospective, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Large Simple Trial Evaluating the Use of BE1116 (4-Factor Prothrombin Complex Concentrate [Kcentra / Beriplex]) to Improve Survival in Patients With Traumatic Injury and Acute Major Bleeding" ($44.9M).