Sage Therapeutics, Inc.

Pharmaceutical & medical device company payment data from CMS Open Payments.

Total Payments
$117.8M
Doctors Paid
8,180
Transactions
25,057
2024 Total
$20.9M

Payment Breakdown by Category

Research$112.2M (95.3%)
Consulting$2.6M (2.2%)
Food & Beverage$440,359 (0.4%)
Royalty/License$398,560 (0.3%)
Travel$210,072 (0.2%)

Payments by Nature

Nature of Payment Amount Transactions Share
Unspecified $112.2M 8,261 95.3%
Consulting Fee $2.6M 814 2.2%
Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program $1.7M 122 1.4%
Food and Beverage $440,359 15,209 0.4%
Royalty or License $398,560 20 0.3%
Travel and Lodging $210,072 572 0.2%
Space rental or facility fees (teaching hospital only) $154,500 8 0.1%
Compensation for serving as faculty or as a speaker for a medical education program $23,057 13 0.0%
Grant $10,000 1 0.0%
Education $2,119 36 0.0%
Gift $252.92 1 0.0%

Payments by Type

Research
$112.2M
8,261 transactions
General
$5.5M
16,796 transactions

Research Studies & Clinical Trials

Study Name Total Paid Doctors Records
A PHASE 3, OPEN-LABEL, 1-YEAR STUDY OF THE SAFETY, TOLERABILITY, AND NEED FOR RE-TREATMENT WITH SAGE-217 IN ADULT SUBJECTS WITH MAJOR DEPRESSIVE DISORDER $19.0M 1 2,294
A PHASE 3, MULTICENTER, DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED STUDY EVALUATING THE EFFICACY OF SAGE-217 IN THE TREATMENT OF ADULT SUBJECTS WITH MAJOR DEPRESSIVE DISORDER $12.8M 0 1,334
A COMPARATIVE STUDY OF SAGE-217 PLUS SERTRALINE VERSUS PLACEBO PLUS SERTRALINE IN ADULTS WITH MAJOR DEPRESSIVE DISORDER $10.3M 0 846
A Phase 3, Open-Label, 1-Year Study of the Safety, Tolerability, and Need for Re-Treatment with SAGE-217 in Adult Subjects with Major Depressive Disorder $7.1M 0 119
A STUDY TO EVALUATE THE EFFICACY AND SAFETY OF SAGE-217 IN PARTICIPANTS WITH SEVERE POSTPARTUM DEPRESSION (PPD) $4.7M 0 918
Study to Evaluate SAGE-324 in Participants With Essential Tremors $4.3M 0 89
A Study to Evaluate the Effect of SAGE-718 on Cognitive Function in Participants With Huntington's Disease (HD) $3.8M 0 51
217-MDD-303 $3.7M 1 259
A PHASE 1, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, COMBINED SINGLE AND MULTIPLE ASCENDING DOSE STUDY TO ASSESS THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF SAGE-904 ORAL SOLUTION IN HEALTHY SUBJECTS $3.0M 0 50
A Study to Evaluate the Long-term Safety and Tolerability of SAGE-324 in Participants With Essential Tremor $2.7M 0 66
A PHASE 1, OPEN-LABEL, 3-PART, 2-PERIOD, FIXED-SEQUENCE STUDY TO EVALUATE THE EFFECT OF RIFAMPIN, PRIMIDONE, AND ITRACONAZOLE ON THE PHARMACOKINETICS, SAFETY, AND TOLERABILITY OF SAGE-324 IN HEALTHY PARTICIPANTS $2.3M 0 21
A PHASE 2, DOUBLE-BLIND, PLACEBO-CONTROLLED, RANDOMIZED, DOSE-RANGING STUDY EVALUATING THE EFFICACY, SAFETY, AND TOLERABILITY OF SAGE-324 MONOTHERAPY AND ADJUNCTIVE THERAPY WITH PROPRANOLOL IN THE TREATMENT OF INDIVIDUALS WITH ESSENTIAL TREMOR $2.0M 0 312
A Study to Evaluate the Effects of SAGE-718 in Participants With Parkinson's Disease Cognitive Impairment $1.7M 0 28
A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE THE EFFECTS OF SAGE-718 IN PARTICIPANTS WITH MILD COGNITIVE IMPAIRMENT OR MILD DEMENTIA DUE TO ALZHEIMER'S DISEASE $1.6M 0 27
NEUROCOGNITIVE EFFECTS, PHARMACOKINETICS, AND SAFETY OF SAGE-217 50 MG ADMINISTERED ALONE AND WITH ALPRAZOLAM OR ETHANOL IN HEALTHY PARTICIPANTS $1.4M 0 44
A Study to Evaluate the Effects of SAGE-718 in Participants With Mild Cognitive Impairment or Mild Dementia Due to Alzheimer's Disease (AD) $1.3M 0 16
A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effects of SAGE-718 in Participants With Mild Cognitive Impairment or Mild Dementia Due to Alzheimer's Disease $1.3M 0 27
217-MDD-304 $1.3M 0 117
A 28-Day Randomized, Placebo-Controlled, Double-Blind, Parallel Groups and Normative Comparison Study to Evaluate the Effect of SAGE-718 on Functioning Capacity in Participants With Huntington's Disease $1.1M 0 16
AN OPEN-LABEL SINGLE-DOSE STUDY TO ASSESS THE ABSORPTION, DISTRIBUTION, METABOLISM, EXCRETION, AND MASS BALANCEOF SAGE-718 ORAL SOLUTION IN HEALTHY ADULT MEN $1.1M 0 9
A PHASE 3, MULTICENTER, OPEN-LABEL SAFETY STUDY TO EVALUATE THE LONG-TERM SAFETY AND TOLERABILITY OF SAGE-718 IN PARTICIPANTS WITH HUNTINGTON'S DISEASE $1.0M 0 18
A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY OF THE SAFETY, TOLERABILITY, AND EFFICACY OF SAGE-217 COMPARED TO PLACEBO IN ADULT SUBJECTS WITH COMORBID MAJOR DEPRESSIVE DISORDER AND INSOMNIA $1.0M 0 171
A RANDOMIZED, DOUBLE-BLIND, ACTIVE-AND-PLACEBO CONTROLLED, 6-WAY CROSSOVER STUDY TO DETERMINE THE ABUSE POTENTIAL OF ORALLY ADMINISTERED SAGE-217 IN HEALTHY, NONDEPENDENT, RECREATIONAL CENTRAL NERVOUS SYSTEM DEPRESSANT USERS $1.0M 0 8
A 28-DAY RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLIND, PARALLEL GROUPS AND NORMATIVE COMPARISON STUDY TO EVALUATE THE EFFECT OF SAGE-718 ON FUNCTIONING CAPACITY IN PARTICIPANTS WITH HUNTINGTON'S DISEASE $924,810 0 16
A MULTICENTER, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY EVALUATING THE EFFICACY, SAFETY, TOLERABILITY, AND PHARMACOKINETICS OF BREXANOLONE IN THE TREATMENT OF ADOLESCENT FEMALE SUBJECTS WITH POSTPARTUM DEPRESSION $890,069 2 80
A STUDY TO EVALUATE THE EFFECT OF SAGE-718 ON COGNITIVE FUNCTION IN PARTICIPANTS WITH HUNTINGTON'S DISEASE (HD) $882,141 0 50
A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE THE EFFECTS OF SAGE-718 IN PARKINSON'S DISEASE COGNITIVE IMPAIRMENT $876,658 0 23
A SINGLE-BLIND, 2-PERIOD, FIXED-SEQUENCE STUDY TO EVALUATE THE PHARMACOKINETICSOF PITAVASTATIN AND PITAVASTATIN LACTONE METABOLITE IN THE PRESENCE ANDABSENCE OF SAGE-324 AND THE SAFETY AND TOLERABILITY OF SAGE-324 IN HEALTHYPARTICIPANTS $871,659 0 1
A Phase 3, Multicenter, Open-label Safety Study to Evaluate the Long-term Safety and Tolerability of SAGE-718 in Participants With Huntington's Disease $823,368 0 20
217-MDD-302 $803,964 1 127

Payments by Medical Specialty

Specialty Total Paid Doctors Avg/Doctor
Psychiatry $3.2M 606 $5,243
Internal Medicine $565,477 58 $9,750
Neurology $514,818 77 $6,686
Obstetrics & Gynecology $282,377 3,056 $92.40
Family Medicine $128,709 167 $770.71
Family $50,612 740 $68.39
Gynecologic Oncology $40,991 7 $5,856
Student in an Organized Health Care Education/Training Program $36,341 342 $106.26
Specialist $31,577 144 $219.29
Psychiatric/Mental Health $23,747 437 $54.34
Nurse Practitioner $23,654 310 $76.30
Physician Assistant $18,936 303 $62.49
Critical Care Medicine $17,069 8 $2,134
Women's Health $15,754 350 $45.01
Advanced Practice Midwife $15,016 358 $41.94
Anesthesiology $12,253 16 $765.84
Geriatric Psychiatry $12,047 6 $2,008
Registered Nurse $11,733 208 $56.41
Pulmonary Disease $11,647 4 $2,912
Maternal & Fetal Medicine $10,800 24 $450.01
Neurology with Special Qualifications in Child Neurology $9,675 1 $9,675
Radiation Oncology $9,500 1 $9,500
Adult Health $7,293 61 $119.55
Sleep Medicine $7,130 2 $3,565
Hematology & Oncology $6,750 1 $6,750
Medical $5,434 89 $61.06
Psychosomatic Medicine $5,258 5 $1,052
Neurodevelopmental Disabilities $5,250 1 $5,250
Pediatrics $4,661 56 $83.22
Neuromuscular Medicine $4,654 3 $1,551
Obstetrics $4,391 96 $45.74
Gynecology $3,804 98 $38.81
Gastroenterology $3,380 2 $1,690
Midwife $3,113 83 $37.50
Anatomic Pathology $2,952 1 $2,952
Neonatal-Perinatal Medicine $2,648 3 $882.55
Acute Care $2,231 25 $89.23
Otology & Neurotology $2,224 1 $2,224
Child & Adolescent Psychiatry $2,212 50 $44.24
Primary Care $2,068 27 $76.59
Nephrology $2,061 1 $2,061
Endocrinology, Diabetes & Metabolism $1,800 1 $1,800
Psychiatric/Mental Health, Adult $1,737 8 $217.15
Emergency Medicine $1,728 9 $191.98
Health Maintenance Organization $1,688 1 $1,688
Behavioral Neurology & Neuropsychiatry $1,443 6 $240.55
Addiction Medicine $1,328 15 $88.54
Surgical $1,133 18 $62.92
Gerontology $1,106 12 $92.17
Pain Medicine $831.10 4 $207.78
Reproductive Endocrinology $783.24 10 $78.32
General Practice $699.51 17 $41.15
Community Health $574.09 7 $82.01
Nurse Anesthetist, Certified Registered $569.61 5 $113.92
Women's Health Care, Ambulatory $552.11 12 $46.01
Forensic Psychiatry $465.84 2 $232.92
Psychiatric/Mental Health, Child & Adolescent $457.41 6 $76.24
Legal Medicine $430.36 7 $61.48
Urogynecology and Reconstructive Pelvic Surgery $370.29 13 $28.48
Clinical Genetics (M.D.) $358.00 1 $358.00
Hospitalist $340.29 9 $37.81
Occupational Health $330.31 3 $110.10
Maternal Newborn $326.46 10 $32.65
Physical Medicine & Rehabilitation $316.71 3 $105.57
Obstetric, Inpatient $309.58 10 $30.96
Medical-Surgical $280.59 3 $93.53
Dermatology $277.96 3 $92.65
Hospice and Palliative Medicine $276.27 6 $46.04
Lactation Consultant $245.43 4 $61.36
Addiction Psychiatry $240.08 5 $48.02
Clinical Nurse Specialist $239.54 2 $119.77
Family Health $232.04 3 $77.35
Neurological Surgery $218.25 1 $218.25
Mental Health $217.74 6 $36.29
Spinal Cord Injury Medicine $210.77 1 $210.77
Emergency $193.05 2 $96.53
Diagnostic Radiology $189.47 3 $63.16
Foot & Ankle Surgery $175.16 1 $175.16
Surgery $166.47 5 $33.29
Psychiatric Hospital $163.20 2 $81.60
Neonatal Intensive Care $159.01 3 $53.00
Geriatric Medicine $154.64 3 $51.55
Infectious Disease $145.40 4 $36.35
Pain Management $143.33 1 $143.33
Clinical $123.34 1 $123.34
School $112.63 1 $112.63
Clinical Neurophysiology $102.80 1 $102.80
Foot and Ankle Surgery $102.80 1 $102.80
MOHS-Micrographic Surgery $102.80 1 $102.80
Otolaryngology $102.80 1 $102.80
Licensed Practical Nurse $100.83 1 $100.83
Ophthalmology $97.15 1 $97.15
Hematology $89.49 2 $44.75
Perinatal $86.99 4 $21.75
Ambulatory Care $77.79 2 $38.89
Vascular Surgery $75.44 1 $75.44
Wound Care $72.25 1 $72.25
Plastic Surgery $67.43 1 $67.43
Multi-Specialty $66.14 1 $66.14
Professional $62.46 3 $20.82
Chiropractor $59.49 1 $59.49
Neonatal $59.30 3 $19.77
Midwife, Lay $57.13 2 $28.56
Procedural Dermatology $55.65 1 $55.65
Sports Medicine $49.54 1 $49.54
Emergency Medical Services $41.86 2 $20.93
Vascular & Interventional Radiology $40.19 1 $40.19
Adolescent Medicine $40.13 2 $20.06
Adult Medicine $38.74 2 $19.37
Registered Nurse First Assistant $38.28 2 $19.14
Surgery of the Hand $35.61 1 $35.61
Doula $33.87 2 $16.94
Allergy $33.82 1 $33.82
Social Worker $30.60 1 $30.60
Addiction (Substance Use Disorder) $30.17 2 $15.08
Obstetric, High-Risk $30.10 1 $30.10
Counselor $28.08 1 $28.08
Athletic Trainer $25.06 1 $25.06
Rehabilitation Practitioner $22.43 1 $22.43
Interventional Cardiology $22.42 1 $22.42
Acupuncturist $20.53 1 $20.53
Undersea and Hyperbaric Medicine $19.34 1 $19.34
Military Health Care Provider $18.77 1 $18.77
Obesity Medicine $17.87 1 $17.87
Behavior Analyst $17.47 1 $17.47
Continuing Education/Staff Development $16.30 1 $16.30
Psychiatric/Mental Health, Community $16.19 1 $16.19
Home Health $15.60 1 $15.60
Urology $15.47 1 $15.47
Psychologist $15.24 1 $15.24
Dentist $13.47 1 $13.47
Prescribing (Medical) $12.13 1 $12.13
Interventional Pain Medicine $11.63 1 $11.63
Complex Family Planning $11.11 1 $11.11

Top Paid Doctors

Doctor Specialty Location Total 2024
Dr. Steven Paul, M.d, M.D Psychiatry Carmel, IN $1.4M $0
Dr. Howard Uderman, M.d, M.D Internal Medicine Lakewood, NJ $509,555 $0
Dr. Donald Garcia, Md, MD Psychiatry Austin, TX $213,591 $0
Charles Nemeroff, Md Phd, MD PHD Psychiatry Austin, TX $183,262 $0
Dr. David Rubinow, Md, MD Psychiatry Chapel Hill, NC $175,031 $0
Dr. Andrew Cole, Md, MD Neurology Boston, MA $168,720 $0
David Sheehan, Md, MD Psychiatry Tampa, FL $153,974 $0
Dr. Daniel Weinberger, M.d, M.D Neurology Washington, DC $151,062 $0
Alan Schatzberg, Md, MD Psychiatry Stanford, CA $149,909 $0
Dr. Kerry Ressler, Md,Phd, MD,PHD Psychiatry Atlanta, GA $144,215 $0
Dr. Brent Allan, Do, DO Family Medicine Paradise Valley, AZ $107,700 $0
K Ranga Krishnan, M.d, M.D Psychiatry Chicago, IL $71,680 $0
Dr. Bassem Maximos, Md, Mph, Pa, MD, MPH, PA Obstetrics & Gynecology League City, TX $58,332 $0
Anita Clayton, M.d, M.D Psychiatry Charlottesville, VA $43,429 $0
Dr. Jason James, M.d, M.D Obstetrics & Gynecology Miami, FL $40,941 $0
David Silver, M.d, M.D Gynecologic Oncology Camp Hill, PA $40,672 $0
Andrew Cutler, Md, MD Psychiatry Lakewood Ranch, FL $38,456 $0
Asha Nayak, M.d., Ph.d, M.D., PH.D Internal Medicine Palo Alto, CA $38,359 $0
Dr. Charles Zorumski, Md, MD Psychiatry Saint Louis, MO $33,027 $0
Madhukar Trivedi, Md, MD Psychiatry Dallas, TX $24,463 $0
Dr. Anthony Rothschild, M.d, M.D Psychiatry Worcester, MA $22,138 $0
Cynthia Epperson, Md, MD Psychiatry Aurora, CO $20,487 $0
Dr. Stephen Stahl, Md, MD Specialist Carlsbad, CA $19,144 $0
Dr. Elan Louis, M.d, M.D Neurology Dallas, TX $18,507 $0
Nicole Sparks, M.d, M.D Student in an Organized Health Care Education/Training Program Johns Creek, GA $18,200 $0

Top Products

  • ZULRESSO $5.1M
  • ZURZUVAE $4.9M

Associated Products (4)

Payment Categories

  • Food & Beverage $440,359
  • Consulting $2.6M
  • Travel & Lodging $210,072
  • Research $112.2M
  • Royalties $398,560

About Sage Therapeutics, Inc.

Sage Therapeutics, Inc. has made $117.8M in payments to 8,180 healthcare providers, recorded across 25,057 transactions in the CMS Open Payments database. In 2024, the company paid $20.9M. The top product by payment volume is ZULRESSO ($5.1M).

Payments were distributed across 134 medical specialties. The top specialty by payment amount is Psychiatry ($3.2M to 606 doctors).

Payment categories include: Food & Beverage ($440,359), Consulting ($2.6M), Research ($112.2M), Travel & Lodging ($210,072), Royalties ($398,560).

Sage Therapeutics, Inc. is associated with 4 products in the CMS Open Payments database, including ZURZUVAE, ZULRESSO, and Zulresso.