OPKO Pharmaceuticals, LLC

Pharmaceutical & medical device company payment data from CMS Open Payments.

Total Payments
$14.2M
Doctors Paid
6,949
Transactions
55,304
2024 Total
$740,737

Payment Breakdown by Category

Research$12.4M (87.5%)
Food & Beverage$746,401 (5.2%)
Consulting$403,864 (2.8%)
Travel$12,316 (0.1%)

Payments by Nature

Nature of Payment Amount Transactions Share
Unspecified $12.4M 703 87.5%
Food and Beverage $746,401 41,379 5.2%
Consulting Fee $403,864 70 2.8%
Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program $350,676 128 2.5%
Education $211,941 12,921 1.5%
Honoraria $39,923 35 0.3%
Space rental or facility fees (teaching hospital only) $14,193 13 0.1%
Travel and Lodging $12,316 53 0.1%
Gift $9.90 2 0.0%

Payments by Type

Research
$12.4M
703 transactions
General
$1.8M
54,601 transactions

Research Studies & Clinical Trials

Study Name Total Paid Doctors Records
Safety and Efficacy of Rayaldee for Treating Mild to Moderate COVID-19 $3.4M 1 110
Repeated-dose Safety, Efficacy, PK and PD of CTAP101, IR Calcifediol, High-dose Cholecalciferol, and Paricalcitol Plus Low-dose Cholecalciferol in Patients With SHPT, CKD 3-4 and VDI $3.2M 0 15
Safety, Efficacy, PK and PD of CTAP101 (Calcifediol) ER Capsules for SHPT in HD Patients VDI $1.4M 0 165
A PHASE 3, OPEN-LABEL, RANDOMIZED, MULTICENTER, 12 MONTHS, EFFICACY AND SAFETY STUDY OF WEEKLY MOD-4023 COMPARED TO DAILY GENOTROPIN THERAPY IN PRE-PUBERTAL CHILDREN WITH GROWTH HORMONE DEFICIENCY $1.2M 1 115
Effects and Safety of OPK-88004 Doses in Men With Signs and Symptoms of Benign Prostatic Hyperplasia (BPH) $1.1M 0 150
Safety and Efficacy Phase 3 Study of Long-acting hGH (MOD-4023) in Growth Hormone Deficient Children $499,967 0 17
A Clinical Study Investigating the Comparability of Somatrogon in Two Different Drug Product Presentations $457,327 0 7
An Open-Label, Repeated-Dose Safety, Efficacy, Pharmacokinetic and Pharmacodynamic Study of Oral CTAP101 Capsules, Immediate- Release (IR) Calcifediol, High-Dose Cholecalciferol, and Paricalcitol Plus Low-Dose Cholecalciferol in Patients With Secondary Hyperparathyroidism, Stage 3 or 4 Chronic Kidney Disease and Vitamin D Insufficiency $429,247 0 10
AN OPEN-LABEL, REPEATED-DOSE SAFETY, EFFICACY, PHARMACOKINETIC AND PHARMACODYNAMIC STUDY OF ORAL CTAP101 CAPSULES, IMMEDIATE- RELEASE (IR) CALCIFEDIOL, HIGH-DOSE CHOLECALCIFEROL, AND PARICALCITOL PLUS LOW-DOSE CHOLECALCIFEROL IN PATIENTS WITH SECONDARY HYPERPARATHYROIDISM, STAGE 3 OR 4 CHRONIC KIDNEY DISEASE AND VITAMIN D INSUFFICIENCY $179,217 0 17
Safety, Efficacy, PK and PD of CTAP101 (calcifediol) ER Capsules for SHPT in HD Patients VDI $161,084 0 21
Safety and Efficacy Study of MOD-4023 to Treat Children With Growth Hormone Deficiency $123,491 0 26
Repeated-dose Safety, Efficacy, Pharmacokinetic and Pharmacodynamic of CTAP101, Immediate-release Calcifediol, High-dose Cholecalciferol, and Paricalcitol Plus Low-dose Cholecalciferol in Patients With Secondary Hyperparathyroidism, Chronic Kidney Disease 3-4 and Vitamin D Insufficiency $70,651 0 20
SAFETY AND EFFICACY OF RAYALDEE FOR TREATING MILD TO MODERATE COVID-19 $35,886 0 2
Safety and dose finding study of different MOD-4023 dose levels compared to daily r-hGH therapy in pre-pubertal growth hormone deficient children $33,414 0 6
A MULTI-CENTER STUDY TO EVALUATE THE EFFICACY, SAFETY AND PHARMACOKINETICS OF CTAP101 EXTENDED-RELEASE CAPSULES TO TREAT SECONDARY HYPERPARATHYROIDISM IN PEDIATRIC SUBJECTS OF AGES 8 TO <18 YEARS WITH STAGE 3 OR 4 CHRONIC KIDNEY DISEASE AND VITAMIN D INSUFFICIENCY. $26,250 0 3
CTAP101?CL?2010 $24,200 0 5
Phase 3 Safety and Efficacy Study of CTAP101 Extended-release Capsules in Children With Secondary Hyperparathyroidism $20,205 1 2
SAFETY AND DOSE FINDING STUDY OF DIFFERENT MOD-4023 DOSE LEVELS COMPARED TO DAILY R-HGH THERAPY IN PRE-PUBERTAL GROWTH HORMONE DEFICIENT CHILDREN $14,409 0 1
SAFETY, EFFICACY, PK AND PD OF CTAP101 (CALCIFEDIOL) ER CAPSULES FOR SHPT IN HD PATIENTS VDI $11,000 0 6
CTAP101_CL_2010 $8,950 0 2
A phase 1/2A, OPEN-LABEL, MULTICENTER, DOSE ESCALATION STUDY TO ASSESS THE SAFETY, PHARMACOKINETICS AND PHARMACODYNAMICS PROFILE OF A LONG-ACTING RECOMBINANT FACTOR VIIA (MOD-5014) IN ADULT MEN WITH HEMOPHILIA A OR B $8,029 0 1
A phase 1/2A, OPEN-LABEL, MULTICARE, DOSE ESCALATION STUDY TO ASSESS THE SAFETY, PHARMACOKINETICS AND PHARMACODYNAMICS PROFILE OF A LONG-ACTING RECOMBINANT FACTOR VIIA (MOD-5014) IN ADULT MEN WITH HEMOPHILIA A OR B $3,196 0 2

Payments by Medical Specialty

Specialty Total Paid Doctors Avg/Doctor
Nephrology $799,531 3,194 $250.32
Pediatric Endocrinology $280,474 3 $93,491
Internal Medicine $272,127 1,194 $227.91
Critical Care Medicine $65,949 24 $2,748
Specialist $62,600 177 $353.67
Family Medicine $47,076 197 $238.97
Pediatrics $43,927 19 $2,312
Family $39,168 487 $80.43
Nurse Practitioner $28,931 252 $114.80
Student in an Organized Health Care Education/Training Program $19,938 159 $125.40
Endocrinology, Diabetes & Metabolism $18,356 225 $81.58
Diagnostic Radiology $15,094 11 $1,372
Physician Assistant $10,845 132 $82.16
Adult Health $8,352 73 $114.41
Acute Care $8,005 88 $90.97
Hospitalist $6,224 52 $119.69
Medical $4,853 63 $77.04
Registered Nurse $3,161 40 $79.03
Hematology & Oncology $2,746 8 $343.28
Gerontology $2,512 36 $69.77
Primary Care $2,309 22 $104.94
Medical Oncology $2,193 2 $1,096
Pediatric Hematology-Oncology $2,000 1 $2,000
Emergency Medicine $1,977 20 $98.85
Urology $1,348 15 $89.85
Surgery $1,140 12 $95.04
Gastroenterology $1,059 15 $70.62
General Practice $1,005 25 $40.20
Neurological Surgery $893.44 2 $446.72
Cardiovascular Disease $761.03 21 $36.24
Vascular Surgery $749.97 6 $125.00
Pulmonary Disease $718.82 12 $59.90
Infectious Disease $680.83 13 $52.37
Geriatric Medicine $663.53 17 $39.03
Legal Medicine $640.93 3 $213.64
Pediatric Nephrology $565.24 4 $141.31
Dermatology $558.39 5 $111.68
Dentist $546.68 8 $68.34
Neurology $543.80 11 $49.44
Anesthesiology $537.86 7 $76.84
Registered Nurse First Assistant $521.90 1 $521.90
Rheumatology $462.66 12 $38.56
Otolaryngology $417.39 5 $83.48
Clinical Nurse Specialist $411.91 3 $137.30
Graphics Designer $405.33 1 $405.33
Ophthalmology $400.63 4 $100.16
General Acute Care Hospital $356.56 2 $178.28
Obstetrics & Gynecology $317.32 7 $45.33
Adult Medicine $302.32 5 $60.46
Psychiatry $299.42 7 $42.77
Foot & Ankle Surgery $269.85 4 $67.46
Surgical Oncology $248.24 1 $248.24
Orthopaedic Surgery $238.77 4 $59.69
Colon & Rectal Surgery $232.37 2 $116.19
Sports Medicine $210.22 5 $42.04
Nuclear Medicine $198.30 1 $198.30
Hematology $190.47 3 $63.49
Emergency $185.93 2 $92.97
Anatomic Pathology & Clinical Pathology $185.49 6 $30.92
Physical Medicine & Rehabilitation $179.83 4 $44.96
Surgical $171.04 4 $42.76
Optometrist $165.28 5 $33.06
Hypertension Specialist $162.76 3 $54.25
Allergy & Immunology $159.55 5 $31.91
Preferred Provider Organization $149.97 1 $149.97
Infusion Therapy $124.92 1 $124.92
Prosthodontics $111.27 1 $111.27
Blood Banking & Transfusion Medicine $98.84 1 $98.84
Pediatric Rheumatology $98.84 1 $98.84
Hospice and Palliative Medicine $96.40 2 $48.20
Sleep Medicine $95.10 1 $95.10
Addiction Medicine $94.66 1 $94.66
Neurology with Special Qualifications in Child Neurology $90.81 1 $90.81
Hepatology $89.53 1 $89.53
Transplant Surgery $81.04 3 $27.01
Podiatrist $77.38 4 $19.35
School $75.01 1 $75.01
Otolaryngology/Facial Plastic Surgery $74.54 1 $74.54
Chiropractor $73.85 4 $18.46
Oncology $70.69 1 $70.69
Plastic Surgery within the Head & Neck $65.62 1 $65.62
Thoracic Surgery (Cardiothoracic Vascular Surgery) $62.77 1 $62.77
Retina Specialist $62.32 2 $31.16
Pediatric Pulmonology $58.60 1 $58.60
Interventional Cardiology $57.81 2 $28.91
Occupational Medicine $53.72 2 $26.86
Pediatric Dentistry $52.36 1 $52.36
Pain Medicine $50.89 2 $25.45
Diabetes Educator $47.62 1 $47.62
Military Health Care Provider $42.86 1 $42.86
Emergency Medical Services $40.18 1 $40.18
Medical-Surgical $38.69 2 $19.35
Obesity Medicine $37.61 2 $18.81
Advanced Heart Failure and Transplant Cardiology $37.33 1 $37.33
Allergy $35.99 1 $35.99
Adult Reconstructive Orthopaedic Surgery $31.36 2 $15.68
Psychiatric/Mental Health $30.25 1 $30.25
Foot Surgery $25.00 2 $12.50
Advanced Practice Midwife $22.33 1 $22.33
Adolescent Medicine $22.05 1 $22.05
Gynecologic Oncology $21.90 1 $21.90
Radiation Oncology $21.64 1 $21.64
Women's Health $20.71 1 $20.71
Addiction (Substance Use Disorder) $19.87 1 $19.87
Plastic and Reconstructive Surgery $19.64 1 $19.64
Adult Congenital Heart Disease $19.51 1 $19.51
Clinical Pathology/Laboratory Medicine $19.15 1 $19.15
Pediatric Emergency Medicine $18.37 1 $18.37
Child Abuse Pediatrics $16.76 1 $16.76
Occupational Therapy Assistant $16.64 1 $16.64
Neonatal $16.40 1 $16.40
Neuromusculoskeletal Medicine, Sports Medicine $15.35 1 $15.35
Gynecology $15.15 1 $15.15
Mental Health (Including Community Mental Health Center) $14.89 1 $14.89
Neonatal-Perinatal Medicine $14.23 1 $14.23
Family Health $14.16 1 $14.16
Oral and Maxillofacial Surgery $13.55 1 $13.55
Child & Adolescent Psychiatry $12.76 1 $12.76

Top Paid Doctors

Doctor Specialty Location Total 2024
Lawrence Silverman, Md, MD Pediatric Endocrinology Morristown, NJ $228,705 $0
Dr. Anis Rauf, Do, DO Critical Care Medicine Hinsdale, IL $64,477 $0
Dr. Judith Ross, Md, MD Pediatric Endocrinology Philadelphia, PA $50,397 $0
Craig Alter, M.d, M.D Pediatrics Philadelphia, PA $42,400 $0
Stuart Sprague, Do, DO Nephrology Evanston, IL $39,243 $0
Dr. Varshasb Broumand, M.d, M.D Internal Medicine San Antonio, TX $38,173 $0
Robert Rapaport, M.d, M.D Specialist New York, NY $36,725 $0
Dr. Matt Rosenberg, M.d, M.D Family Medicine Jackson, MI $29,000 $0
Erdal Sarac, M.d, M.D Nephrology Poland, OH $21,402 $0
John Heymach, M.d, M.D Internal Medicine Houston, TX $20,000 $0
Ronald Levy, Md, MD Internal Medicine Stanford, CA $20,000 $0
Dr. Michael Germain, Md, MD Nephrology Springfield, MA $17,237 $0
Alexander Swan, Md, MD Nephrology Avenel, NJ $14,925 $0
Eric Rubin, Md, MD Diagnostic Radiology New Orleans, LA $14,600 $0
Nelson Kopyt, Do, DO Nephrology Allentown, PA $13,354 $0
Arnold Silva, Md, Phd, MD, PHD Internal Medicine Meridian, ID $11,525 $0
Unknown Provider $11,427 $0
Dr. Harry Dounis, Do, DO Nephrology Neptune, NJ $11,285 $0
Dr. Leonard Stern, M.d, M.D Nephrology New York, NY $8,897 $0
Dr. Christopher Kwoh, M.d, M.D Nephrology Houston, TX $7,922 $0
Dr. Geoffrey Block, Md, MD Nephrology Lone Tree, CO $6,671 $0
Jay Wish, Md, MD Nephrology Indianapolis, IN $6,145 $0
William Kendrick, M.d, M.D Nephrology Greenville, NC $6,030 $0
Dr. Donald Molony, M.d, M.D Internal Medicine Houston, TX $5,846 $0
Dr. Spiros Arbes, Md, MD Nephrology Eatontown, NJ $5,714 $0

Top Products

  • RAYALDEE $6.0M
  • Rayaldee $3.9M

Associated Products (8)

Payment Categories

  • Food & Beverage $746,401
  • Consulting $403,864
  • Travel & Lodging $12,316
  • Research $12.4M

About OPKO Pharmaceuticals, LLC

OPKO Pharmaceuticals, LLC has made $14.2M in payments to 6,949 healthcare providers, recorded across 55,304 transactions in the CMS Open Payments database. In 2024, the company paid $740,737. The top product by payment volume is RAYALDEE ($6.0M).

Payments were distributed across 118 medical specialties. The top specialty by payment amount is Nephrology ($799,531 to 3,194 doctors).

Payment categories include: Food & Beverage ($746,401), Consulting ($403,864), Research ($12.4M), Travel & Lodging ($12,316).

OPKO Pharmaceuticals, LLC is associated with 8 products in the CMS Open Payments database, including RAYALDEE, Rayaldee, and Benign Prostatic Hyperplasia.